NEWS
Curry spice boosts exercise performance in mice with heart failure
POSTED 30 Nov 2018 . BY Jane Kitchen
New research suggests that curcumin, a main ingredient in curry, may improve exercise intolerance related to heart failure. The study is published ahead of print in the Journal of Applied Physiology.

Curcumin, a chemical that comes from the turmeric plant, has been used as a traditional Asian medicine for centuries, primarily to treat gastrointestinal ailments and skin wounds. Studies increasingly suggest that the compound may prevent or limit muscle wasting associated with a number of health conditions, including heart failure.

People with heart failure have a reduced function of the left ventricle – the chamber of the heart that pumps blood out to the rest of the body – called reduced ejection fraction. A decreased ability to exercise (exercise intolerance) is another significant characteristic of heart failure.

Researchers from the University of Nebraska Medical Center in the US examined the effects of curcumin on a mouse model of heart failure with reduced ejection fraction.

One group of mice with heart failure received daily doses of curcumin for 12 weeks, and another group did not receive treatment. The heart failure groups were compared to a control group of healthy mice that received curcumin and an untreated control group.

The research team measured the exercise capacity of all the mice before and after curcumin treatment. The researchers also examined muscle fiber samples to assess enzyme expression levels. They found that expression of Nrf2 – a protein that regulates the expression of antioxidant enzymes – increased, and levels of antioxidant enzymes improved in the animals with heart failure that were given curcumin.

In addition, both groups that received curcumin – even the animals without heart failure – had improved exercise capacity when compared with the untreated groups, suggesting the effects of curcumin on skeletal muscle is not exclusive to heart failure.

"These data suggest that activation of Nrf2 in skeletal muscle may represent a novel therapeutic strategy to improve ... quality of life" in people with heart failure with reduced ejection fraction, the researchers wrote.

 


ADVERTISE . CONTACT US

Leisure Media, Portmill House, Portmill Lane,
Hitchin, Hertfordshire SG5 1DJ Tel: +44 (0)1462 431385

©Cybertrek 2019

ABOUT LEISURE MEDIA
LEISURE MEDIA MAGAZINES
LEISURE MEDIA HANDBOOKS
LEISURE MEDIA WEBSITES
LEISURE MEDIA PRODUCT SEARCH
PRINT SUBSCRIPTIONS
FREE DIGITAL SUBSCRIPTIONS
 
Spa Business - Curry spice boosts exercise performance in mice with heart failure...
20 Feb 2019 Spa Business: uniting the world of wellness
 
 
HOME
JOBS
NEWS
FEATURES
PRODUCTS
FREE DIGITAL SUBSCRIPTION
PRINT SUBSCRIPTION
ADVERTISE
CONTACT US
Sign up for FREE ezine
Latest news

30 Nov 2018

Curry spice boosts exercise performance in mice with heart failure
BY Jane Kitchen

The research suggested that curcumin could be used to improve exercise capacity and prevent heart failure

The research suggested that curcumin could be used to improve exercise capacity and prevent heart failure

New research suggests that curcumin, a main ingredient in curry, may improve exercise intolerance related to heart failure. The study is published ahead of print in the Journal of Applied Physiology.

Curcumin, a chemical that comes from the turmeric plant, has been used as a traditional Asian medicine for centuries, primarily to treat gastrointestinal ailments and skin wounds. Studies increasingly suggest that the compound may prevent or limit muscle wasting associated with a number of health conditions, including heart failure.

People with heart failure have a reduced function of the left ventricle – the chamber of the heart that pumps blood out to the rest of the body – called reduced ejection fraction. A decreased ability to exercise (exercise intolerance) is another significant characteristic of heart failure.

Researchers from the University of Nebraska Medical Center in the US examined the effects of curcumin on a mouse model of heart failure with reduced ejection fraction.

One group of mice with heart failure received daily doses of curcumin for 12 weeks, and another group did not receive treatment. The heart failure groups were compared to a control group of healthy mice that received curcumin and an untreated control group.

The research team measured the exercise capacity of all the mice before and after curcumin treatment. The researchers also examined muscle fiber samples to assess enzyme expression levels. They found that expression of Nrf2 – a protein that regulates the expression of antioxidant enzymes – increased, and levels of antioxidant enzymes improved in the animals with heart failure that were given curcumin.

In addition, both groups that received curcumin – even the animals without heart failure – had improved exercise capacity when compared with the untreated groups, suggesting the effects of curcumin on skeletal muscle is not exclusive to heart failure.

"These data suggest that activation of Nrf2 in skeletal muscle may represent a novel therapeutic strategy to improve ... quality of life" in people with heart failure with reduced ejection fraction, the researchers wrote.




Connect with
Spa Business
Magazine:
View issue contents
Sign up:
Instant Alerts/zines

Print edition
 

News headlines
Calistoga mud, grape seeds and olive oil: new details revealed for Four Seasons’ upcoming Napa Valley spa
Calistoga mud, grape seeds and olive oil: new details revealed for Four Seasons’ upcoming Napa Valley spa   18 Feb 2019

The Four Seasons Resort and Residences Napa Valley, set to open 1 November, has revealed new details of the California resort and its wellness spa. .... more>>
Mehmet Er returns to Gharieni in new international role
Mehmet Er returns to Gharieni in new international role   18 Feb 2019

Mehmet Er has returned to spa equipment manufacturer Gharieni in the role of international sales manager, after a brief stint working in global sales .... more>>
Vila Vita Parc opens first Sisley Spa in Portugal
Vila Vita Parc opens first Sisley Spa in Portugal   15 Feb 2019

Vila Vita Parc Resort & Spa, a clifftop resort in Portugal’s Algarve, has launched a new Spa by Sisley, the first Sisley-branded spa in Portugal. The .... more>>
Raffles launches new Sleep Rituals programme
Raffles launches new Sleep Rituals programme   14 Feb 2019

Raffles Hotels & Resorts has launched a wellbeing programme designed to help guests unwind and get a peaceful night’s rest. The new Raffles Sleep .... more>>
Speakers announced for Women in Wellness event
Speakers announced for Women in Wellness event   14 Feb 2019

The Women in Wellness Leadership Conference, set to take place on 12 March in New York City, has announced a host of speakers designed to motivate .... more>>
Company profile


Technogym

The company’s offer is represented by the Technogym Ecosystem, which includes a wide range of cardio, strength and functional training equipment.

View full profile>>

Catalogue gallery


Featured Supplier

Get ready to EVOLVE at #ISPA2019

Get ready to EVOLVE at #ISPA2019

The 2019 ISPA Conference & Expo is headed back to Las Vegas between 11 and 13 September 2019. More>>




in this issue

• UK Sport relaxes 'no compromise' stance
• Orangetheory hits billion revenue landmark
• Thameside manor resort gets green light



Spa jobs




Healthy Communities Development Officer
Salary: £31,000
Location: Aberdeen
Company: Sport Aberdeen
Healthy Communities Manager
Salary: Up to £45,000 per annum, for the right person
Location: Aberdeen
Company: Sport Aberdeen
Senior Beauty Therapist
Salary: £21,200 plus commission and amazing benefits
Location: Wiltshire, UK
Company: Center Parcs
Diary dates
Powered by leisurediary.com




24-25 Feb 2019

International Manufacturers & Distributors Forum

ExCeL, London, United Kingdom


24-25 Feb 2019

Active Wellness

ExCeL London, London, United Kingdom



Spa Business magazine 2019 issue 1
Spa Business
2019 issue 1

View issue contents
View on turning pages
Download PDF
  Research: Mind over matter
A new white paper reveals the benefits of numerous spa modalities on mental health. Editor Gerry Bodeker reports More>>
  Spa Programmes: On the menu
Event saunas, sunlight therapy and health and happiness retreats feature in our programming series More>>


Spa Business magazine 2018 issue 4

Spa Business
2018 issue 4

View issue contents
View turning pages
Download PDF
  Finishing touch: Warming up
Saunas help reduce risk of chronic diseases, a new study shows More>>
  Event report: GWS 2018
An Italian inspired Global Wellness Summit featured fashion, food, fitness and spa… and cameos from Hugh Jackman and Oprah Winfrey. Spa Business gives its highlights More>>


Published by The Leisure Media Company Ltd Portmill House, Portmill Lane, Hitchin, Herts SG5 1DJ. Tel: +44 (0)1462 431385 | Contact us | About us | © Cybertrek Ltd