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Innovative studies on cell senescence inspire Comfort Zone’s new approach to anti-ageing
21 Dec 2021
A dermatologist helped to develop the Sublime Skin range /
A dermatologist helped to develop the Sublime Skin range
With the relaunch of Sublime Skin, the Comfort Zone R&R team has further deepened its knowledge of skin ageing mechanisms in order to offer even more complete and effective cosmetic solutions.

The innovation relates to the study and treatment of cellular senescence, a critical phenomenon that accompanies skin ageing and affects all cells and all skin layers, globally and progressively compromising skin vitality and functionality.

Research has found that when cells age and reach the senescence stage, they don’t simply stop stimulating growth factors. Instead, they also release harmful substances, known as SASPs (senescence-associated secretory phenotypes), inflammatory molecules that attack neighbouring cells, causing them to enter a state of premature senescence.

This triggers a chain reaction in the skin’s layers that causes and aggravates wrinkles, dryness and a visible loss of tone.

More specifically, inflammatory molecules (SASPs) in the epidermis alter the turnover causing weakening of the barrier function and a greater water loss.

In the dermis, they compromise the fibroblasts, reducing collagen and elastin production and they cause an increase in metalloproteinases, the enzymes that degrade collagen and elastin, damaging the skin, which becomes less firm and elastic.

In the hypodermis the secretion of inflammatory SASP molecules also reduces adipogenesis, leading to less lipid accumulation, which explains the loss of tissue volume observed with age.

In order to counteract cellular senescence, Comfort Zone has selected Acetyl Hexapeptide-8 for the new Sublime Skin Intensive Serum.

This high tech ingredient reduces the presence of SASPs by 55 per cent and therefore weakens the degeneration caused by senescent cells. Furthermore, the compound blocks the skin neurotransmitter responsible for facial expression, inhibiting muscle contraction and reducing wrinkles and expression lines.

To learn more, head to Comfort Zone’s official website.
Company profile

Comfort Zone

Comfort Zone’s comprehensive face and body range allows clients to experience memorable facials and rituals at day and destination spas.

Read Comfort Zone's full profile here
Suppliers
Comfort Zone

Parma Italy
Conceived in 1996 by Dr Davide Bollati, founder of the Davines Group, a leading Italian certified B Corporation developing and manufacturing sustainable skin and hair care, Comfort Zone offers result-oriented face and body products and professional treatments.
https://www.comfortzoneskin.com/
More details
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Uniting the world of spa & wellness
Get Spa Business and Spa Business insider digital magazines FREE
Sign up here ▸
News   Products   Magazine   Subscribe
PRODUCT NEWS
Innovative studies on cell senescence inspire Comfort Zone’s new approach to anti-ageing
21 Dec 2021
A dermatologist helped to develop the Sublime Skin range
With the relaunch of Sublime Skin, the Comfort Zone R&R team has further deepened its knowledge of skin ageing mechanisms in order to offer even more complete and effective cosmetic solutions.

The innovation relates to the study and treatment of cellular senescence, a critical phenomenon that accompanies skin ageing and affects all cells and all skin layers, globally and progressively compromising skin vitality and functionality.

Research has found that when cells age and reach the senescence stage, they don’t simply stop stimulating growth factors. Instead, they also release harmful substances, known as SASPs (senescence-associated secretory phenotypes), inflammatory molecules that attack neighbouring cells, causing them to enter a state of premature senescence.

This triggers a chain reaction in the skin’s layers that causes and aggravates wrinkles, dryness and a visible loss of tone.

More specifically, inflammatory molecules (SASPs) in the epidermis alter the turnover causing weakening of the barrier function and a greater water loss.

In the dermis, they compromise the fibroblasts, reducing collagen and elastin production and they cause an increase in metalloproteinases, the enzymes that degrade collagen and elastin, damaging the skin, which becomes less firm and elastic.

In the hypodermis the secretion of inflammatory SASP molecules also reduces adipogenesis, leading to less lipid accumulation, which explains the loss of tissue volume observed with age.

In order to counteract cellular senescence, Comfort Zone has selected Acetyl Hexapeptide-8 for the new Sublime Skin Intensive Serum.

This high tech ingredient reduces the presence of SASPs by 55 per cent and therefore weakens the degeneration caused by senescent cells. Furthermore, the compound blocks the skin neurotransmitter responsible for facial expression, inhibiting muscle contraction and reducing wrinkles and expression lines.

To learn more, head to Comfort Zone’s official website.
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Elevate your spa business: master global standards and thrive in Saudi Arabia's tourism boom
Discover how to prepare your spa or wellness facility for the influx of international guests and meet global standards as tourism in Saudi Arabia surges.
How technology can help drive growth for your spa business
It's safe to say that technology is transforming every sector, and the spa, wellness and beauty industries are no exception.
Discover Comfort Zone’s Stand For Regeneration campaign
Comfort Zone's latest initiative, the Stand for Regeneration campaign, consolidates its position as a pioneer in the cosmetics business.
Yon-Ka Paris introduces groundbreaking CBD serum and treatment
A key player in the wellness industry since 1954, Yon-Ka Paris has dedicated its expertise to developing exceptional, naturally rejuvenating and high-performance products which suit modern lifestyles.
Spa and wellness industry to reunite at Forum HOTel&SPA 2024
The 16th edition of the esteemed international spa and hospitality industry event, Forum HOTel&SPA, is rapidly approaching, promising an immersive experience for attendees.
Embrace the future of luxury science-backed skincare with Amra's Micro-Cellular Actives
Amra Skincare has positioned itself at the forefront of dermatological science and introduced its Micro-Cellular Actives line – a range of innovative molecular agents formulated to redefine the brand’s clinically-driven skincare applications for unparalleled results.
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