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Could exercise slow down the negative effects Alzheimer's has on the brain?
POSTED 04 Oct 2019 . BY Tom Walker
Dr. Rong Zhang (left), the lead author of the research, reviewing data of the survey
Regular weekly exercise sessions could delay brain deterioration in people at high risk for Alzheimer's disease.

Research by The University of Texas Southwestern shows that people who had an accumulation of amyloid beta in the brain – the amino acids crucially involved in Alzheimer's disease – experienced slower degeneration in a region of the brain crucial for memory if they exercised regularly for one year.

Amyloid beta is the main component of the amyloid plaques found in the brains of people with Alzheimer's disease.

While the research found that exercise did not prevent the eventual spread of toxic amyloid plaques – blamed for killing neurons in the brains of dementia patients – the findings suggest the possibility that aerobic workouts can at least slow down the effects of the disease if intervention occurs in the early stages.

"Currently, doctors can't prescribe anything if you have amyloid clumping together in the brain," said Dr Rong Zhang, who led the clinical trial.

"If these findings can be replicated in a larger trial, then maybe one day doctors will be telling high-risk patients to start an exercise plan. In fact, there's no harm in doing so now."

Published in the Journal of Alzheimer's Disease, the study compared cognitive function and brain volume between two groups of sedentary older adults with memory issues.

One group undertook aerobic exercise for at least 30 minutes four to five times each week, while another group only took part in flexibility training.

Both groups maintained similar cognitive abilities during the trial in areas, such as memory and problem-solving.

Brain imaging, however, showed that people from the frequent exercise group – who already had amyloid buildup – experienced slightly less volume reduction in their hippocampus, a memory-related brain region that progressively deteriorates as dementia takes hold.

"It's interesting that the brains of participants with amyloid responded more to the aerobic exercise than the others," Zhang added.

"Although the interventions didn't stop the hippocampus from getting smaller, even slowing down the rate of atrophy through exercise could be an exciting revelation."

• To read the full report on the survey, click here.
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Uniting the world of spa & wellness
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News   Products   Magazine   Subscribe
NEWS
Could exercise slow down the negative effects Alzheimer's has on the brain?
POSTED 04 Oct 2019 . BY Tom Walker
Dr. Rong Zhang (left), the lead author of the research, reviewing data of the survey
Regular weekly exercise sessions could delay brain deterioration in people at high risk for Alzheimer's disease.

Research by The University of Texas Southwestern shows that people who had an accumulation of amyloid beta in the brain – the amino acids crucially involved in Alzheimer's disease – experienced slower degeneration in a region of the brain crucial for memory if they exercised regularly for one year.

Amyloid beta is the main component of the amyloid plaques found in the brains of people with Alzheimer's disease.

While the research found that exercise did not prevent the eventual spread of toxic amyloid plaques – blamed for killing neurons in the brains of dementia patients – the findings suggest the possibility that aerobic workouts can at least slow down the effects of the disease if intervention occurs in the early stages.

"Currently, doctors can't prescribe anything if you have amyloid clumping together in the brain," said Dr Rong Zhang, who led the clinical trial.

"If these findings can be replicated in a larger trial, then maybe one day doctors will be telling high-risk patients to start an exercise plan. In fact, there's no harm in doing so now."

Published in the Journal of Alzheimer's Disease, the study compared cognitive function and brain volume between two groups of sedentary older adults with memory issues.

One group undertook aerobic exercise for at least 30 minutes four to five times each week, while another group only took part in flexibility training.

Both groups maintained similar cognitive abilities during the trial in areas, such as memory and problem-solving.

Brain imaging, however, showed that people from the frequent exercise group – who already had amyloid buildup – experienced slightly less volume reduction in their hippocampus, a memory-related brain region that progressively deteriorates as dementia takes hold.

"It's interesting that the brains of participants with amyloid responded more to the aerobic exercise than the others," Zhang added.

"Although the interventions didn't stop the hippocampus from getting smaller, even slowing down the rate of atrophy through exercise could be an exciting revelation."

• To read the full report on the survey, click here.
RELATED STORIES
Physical exercise 'protects against Alzheimer's'


Physical exercise and keeping fit can protect against the onset of Alzheimer's disease, according to a study by the Centre for Human Psychopharmacology (CHP) at the Swinburne University of Technology in Australia.
MORE NEWS
HCM News: Taking GLP-1s is linked to a decline in physical activity
People taking GLP-1 weight loss medications such as Ozempic, Wegovy, Mounjaro and Zepbound may be losing weight, but they’re also becoming less physically active, according to new research presented at the ENDO 2026 annual meeting of the Endocrine Society
Mubadala makes €1 billion bid for Pierre and Vacances
Abu Dhabi-based investment firm Mubadala Capital has made a binding, fully financed €1 billion offer to acquire Pierre and Vacances SA, the European holiday resort operator behind the continental European Center Parcs business.
Synergy The Retreat Show launches resource for retreat business leaders to showcase specialisms
Global retreat trade show, Synergy The Retreat Show, has launched a resource called The Source, which hosts an open-access online Transformation Series programme.
The SATCC announces first five-day Living with Cancer and Beyond retreat
The Standards Authority for Touch in Cancer Care (SATCC) charity has announced its first five- day Living with Cancer and Beyond retreat, which will be held at Carden Park Hotel and Spa in Cheshire, UK, between 1 and 5 September.
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ADVERTISE . CONTACT US

Leisure Media
Tel: +44 (0)1462 431385

©Cybertrek 2026

ABOUT LEISURE MEDIA
LEISURE MEDIA MAGAZINES
LEISURE MEDIA HANDBOOKS
LEISURE MEDIA WEBSITES
LEISURE MEDIA PRODUCT SEARCH
PRINT SUBSCRIPTIONS
FREE DIGITAL SUBSCRIPTIONS