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NEWS
Research provides insight on potential impact of obesity on the brain
POSTED 08 Aug 2014 . BY Chris Dodd
Obesity is a major problem throughout the developed world, not least in the US and Europe Credit: Shutterstock.com/bikeriderlondon
Obesity could have an impact on how smart we are, after research conducted on mice showed how fat levels may potentially cloud cognitive processes.

In a study conducted at Georgia Regents University, experts monitored a group of obese mice that housed high levels of a chemical substance known as interleukin 1.

The substance is known to be created from fat cells and can lead to inflammation, which was the case when the researchers observed the brains of the mice, finding that the chemical had managed to seep into the hippocampus – an area in the brain which takes care of both learning capabilities and memory function.

The obese mice tested poorly during cognitive tests, with scientists presuming the levels of interleukin 1 and subsequent inflammation had impacted on the mice’s efficiency.

To back up their initial findings, the scientists decided to conduct a small liposuction procedure on the obese mice to remove fat, which led to the specimens performing a lot better on the same cognitive tests they had taken before the removal of the fat.

The results were solidified as the researchers then placed fat pads inside leaner mice, with the animals performing worse than they had done in their previous brain function tests.

The research also provided an insight towards what exercise can do for the function of the brain, with obese mice placed on a daily exercise regime.

They were then compared to a group of sedentary mice after three months, where results showed that despite remaining the same weight as those that didn't take part in exercise, the obese mice had gained lean muscle and lost fat, while they also began to outperform the non-active mice in cognitive tests.

Obviously, the research into the mice does not necessarily stand as evidence for how the human brain could react, but it does offer further weight to a growing and predominantly accepted argument that exercise can help to improve brain function and general health too.

A number of other findings recently have shown the potential benefits of exercise and physical fitness both on children and adults.

One study has shown that physical condition could have an impact on the academic performance of young people, while another has suggested that exercise should be prescribed to improve the health of older women.

Meanwhile, in a study soon to be published in the September 2014 issue of the Journal of Occupational and Environmental Hygiene, obesity has been shown to have a detrimental impact on the endurance of workers when performing many workplace tasks, for example in factory or industrial settings.
RELATED STORIES
  Accepting obesity as the norm goes against our sector's principles: HCM editor Kate Cracknell


Accepting obesity as something to be catered for, rather than a tide to be turned, would go against everything the health and industry believes in, according to Health Club Management editor Kate Cracknell in her August leader column.
  Exercise should be prescribed to improve health of older women, says new study


Research from the Queensland University of Technology's Institute of Health and Biomedical Innovation suggesting that moderate to high intensity activity could be essential to reducing the risk of death in older women.
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  European Court of Justice could define obesity as a disability


The European Court of Justice is considering a test case which could oblige employers to treat obesity as a disability, potentially leaving them with a duty to make adjustments to work environments.
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NEWS
Research provides insight on potential impact of obesity on the brain
POSTED 08 Aug 2014 . BY Chris Dodd
Obesity is a major problem throughout the developed world, not least in the US and Europe Credit: Shutterstock.com/bikeriderlondon
Obesity could have an impact on how smart we are, after research conducted on mice showed how fat levels may potentially cloud cognitive processes.

In a study conducted at Georgia Regents University, experts monitored a group of obese mice that housed high levels of a chemical substance known as interleukin 1.

The substance is known to be created from fat cells and can lead to inflammation, which was the case when the researchers observed the brains of the mice, finding that the chemical had managed to seep into the hippocampus – an area in the brain which takes care of both learning capabilities and memory function.

The obese mice tested poorly during cognitive tests, with scientists presuming the levels of interleukin 1 and subsequent inflammation had impacted on the mice’s efficiency.

To back up their initial findings, the scientists decided to conduct a small liposuction procedure on the obese mice to remove fat, which led to the specimens performing a lot better on the same cognitive tests they had taken before the removal of the fat.

The results were solidified as the researchers then placed fat pads inside leaner mice, with the animals performing worse than they had done in their previous brain function tests.

The research also provided an insight towards what exercise can do for the function of the brain, with obese mice placed on a daily exercise regime.

They were then compared to a group of sedentary mice after three months, where results showed that despite remaining the same weight as those that didn't take part in exercise, the obese mice had gained lean muscle and lost fat, while they also began to outperform the non-active mice in cognitive tests.

Obviously, the research into the mice does not necessarily stand as evidence for how the human brain could react, but it does offer further weight to a growing and predominantly accepted argument that exercise can help to improve brain function and general health too.

A number of other findings recently have shown the potential benefits of exercise and physical fitness both on children and adults.

One study has shown that physical condition could have an impact on the academic performance of young people, while another has suggested that exercise should be prescribed to improve the health of older women.

Meanwhile, in a study soon to be published in the September 2014 issue of the Journal of Occupational and Environmental Hygiene, obesity has been shown to have a detrimental impact on the endurance of workers when performing many workplace tasks, for example in factory or industrial settings.
RELATED STORIES
Accepting obesity as the norm goes against our sector's principles: HCM editor Kate Cracknell


Accepting obesity as something to be catered for, rather than a tide to be turned, would go against everything the health and industry believes in, according to Health Club Management editor Kate Cracknell in her August leader column.
Exercise should be prescribed to improve health of older women, says new study


Research from the Queensland University of Technology's Institute of Health and Biomedical Innovation suggesting that moderate to high intensity activity could be essential to reducing the risk of death in older women.
ukactive says new medical guidelines could cause 'surgery first' mentality to obesity crisis


ukactive CEO David Stalker has raised concerns that people are in danger of promoting a ‘surgery first’ mentality to managing obesity-related conditions in the wake of new draft guidelines from the National Institute of Health and Care Excellence (NICE),which is aiming to reduce debilitating weight problems.
European Court of Justice could define obesity as a disability


The European Court of Justice is considering a test case which could oblige employers to treat obesity as a disability, potentially leaving them with a duty to make adjustments to work environments.
MORE NEWS
ISPA releases full 2026 US Spa Industry Study as annual industry revenue rises by US$1bn
The International Spa Association (ISPA) has published its full 2026 US Spa Industry Study, providing further insights into the region’s total US$1 billion (€855 million, £780 million) industry revenue increase from 2024 to 2025.
Hot spring wellness community Ameyalli sells residences and breaks ground on resort and spa
Ameyalli, the 78-acre wellbeing resort and residential community in Midway in Utah, US, has broken ground on phase two of the hot spring development – the Ameyalli Resort and Spa – which is due to open in 2028.
AI firm Midjourney enters wellness with spa, fitness and body scanning concept
TLee Spas and Wellness has revealed the design concept for a high-tech spa with body mapping scanners to improve public health, for AI company Midjourney.
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FEATURED SUPPLIERS

MSpa Oslo series: a timeless bestseller
The MSpa Oslo series is a perennial bestseller in global markets. With innovative engineering and premium performance, this completely portable spa line-up is expertly designed to meet the needs of customers worldwide. [more...]

Elemis launches its first Red Light Mask, lighting the way to advanced skin health and restoration
Elemis has branched into LED skincare with the launch of its breakthrough Red Light Mask. [more...]
+ More featured suppliers  
COMPANY PROFILES
Elemis

Since 1989, Elemis has been delivering hands-on spa treatments and award-winning skincare to partn [more...]
+ More profiles  
CATALOGUE GALLERY
+ More catalogues  

DIRECTORY
+ More directory  
DIARY

 

23-26 Aug 2026

Elevate Spa Riviera Maya Edition

The Riviera Maya Edition Kanai, Playa del Carmen, Mexico
31 Aug - 02 Sep 2026

SpaTec North America

Pier Sixty Six, Fort Lauderdale, United States
+ More diary  
 


ADVERTISE . CONTACT US

Leisure Media
Tel: +44 (0)1462 431385

©Cybertrek 2026

ABOUT LEISURE MEDIA
LEISURE MEDIA MAGAZINES
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