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NEWS
Exercise stops cancer growth
POSTED 18 Oct 2021 . BY Tom Walker
Myokines can suppress tumour growth in cancer patients who exercise regularly Credit: Shutterstock/​​LightField Studios

Credit: Edith Cowan University
The patients’ levels of anti-cancer myokines increased during the three months of the study
– Professor Robert Newton
Regular exercise creates a 'cancer suppressive environment' in the body, according to research.
A study looked at myokines – proteins which are secreted into blood during exercise
Researchers found that myokins suppress tumour growth and even contribute to the destruction of cancerous cells
The study focused on prostate cancer, but researchers say the mechanism applies to all cancers
Exercise has been highlighted as a crucial weapon in cancer patients’ battle against the disease.

Research from Edith Cowan University (ECU) in Perth, Australia, has found that myokines – proteins that are secreted into the blood during exercise – can suppress the growth of cancer cells and trigger mechanisms that destroy them.

A clinical trial saw obese prostate cancer patients undergo regular exercise training for 12 weeks, giving blood samples before and after the exercise programme.

Researchers then took the samples and applied them directly onto living prostate cancer cells.

Professor Robert Newton, who supervised the research, said the results help explain why cancer progresses more slowly in patients who exercise.

“The patients’ levels of anti-cancer myokines increased in the three months of the study,” he said.

“When we took their pre-exercise blood and their post-exercise blood and placed it over living prostate cancer cells, we saw significant suppression of the growth of those cells from the post-training blood.

“That’s a substantial finding, indicating that regular exercise creates a cancer suppressive environment in the body.”

While myokines signal cancer cells to grow more slowly – or stop growing completely – they were unable to kill the cells by themselves.

However, myokines can team up with other cells in the blood to actively fight cancer.

Research lead, Jin-Soo Kim, said: “Myokines in and of themselves don’t signal the cells to die, but they do signal to our immune cells – T-cells – to attack and kill the cancer cells.”

The study focused on prostate cancer due to it being the most common non-skin cancer among men and the high number of patient fatalities.

Professor Newton, however, said the findings could have a wider impact.

“We believe this mechanism applies to all cancers,” he said.

The findings of the study were published in a report – called Myokine expression and tumour-suppressive effect of serum following 12 weeks of exercise in prostate cancer patients on ADT – which published in Medicine and Science in Sports and Exercise. To read the full report, click here.
Sign up here to get the Spa Business and Spa Business insider weekly ezines and every issue of Spa Business and Spa Business insider magazines free on digital.
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NEWS
Exercise stops cancer growth
POSTED 18 Oct 2021 . BY Tom Walker
Myokines can suppress tumour growth in cancer patients who exercise regularly Credit: Shutterstock/​​LightField Studios
Credit: Edith Cowan University
The patients’ levels of anti-cancer myokines increased during the three months of the study
– Professor Robert Newton
Regular exercise creates a 'cancer suppressive environment' in the body, according to research.
A study looked at myokines – proteins which are secreted into blood during exercise
Researchers found that myokins suppress tumour growth and even contribute to the destruction of cancerous cells
The study focused on prostate cancer, but researchers say the mechanism applies to all cancers
Exercise has been highlighted as a crucial weapon in cancer patients’ battle against the disease.

Research from Edith Cowan University (ECU) in Perth, Australia, has found that myokines – proteins that are secreted into the blood during exercise – can suppress the growth of cancer cells and trigger mechanisms that destroy them.

A clinical trial saw obese prostate cancer patients undergo regular exercise training for 12 weeks, giving blood samples before and after the exercise programme.

Researchers then took the samples and applied them directly onto living prostate cancer cells.

Professor Robert Newton, who supervised the research, said the results help explain why cancer progresses more slowly in patients who exercise.

“The patients’ levels of anti-cancer myokines increased in the three months of the study,” he said.

“When we took their pre-exercise blood and their post-exercise blood and placed it over living prostate cancer cells, we saw significant suppression of the growth of those cells from the post-training blood.

“That’s a substantial finding, indicating that regular exercise creates a cancer suppressive environment in the body.”

While myokines signal cancer cells to grow more slowly – or stop growing completely – they were unable to kill the cells by themselves.

However, myokines can team up with other cells in the blood to actively fight cancer.

Research lead, Jin-Soo Kim, said: “Myokines in and of themselves don’t signal the cells to die, but they do signal to our immune cells – T-cells – to attack and kill the cancer cells.”

The study focused on prostate cancer due to it being the most common non-skin cancer among men and the high number of patient fatalities.

Professor Newton, however, said the findings could have a wider impact.

“We believe this mechanism applies to all cancers,” he said.

The findings of the study were published in a report – called Myokine expression and tumour-suppressive effect of serum following 12 weeks of exercise in prostate cancer patients on ADT – which published in Medicine and Science in Sports and Exercise. To read the full report, click here.
Sign up here to get the Spa Business and Spa Business insider weekly ezines and every issue of Spa Business and Spa Business insider magazines free on digital.
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FEATURE: Industry insights: On the road to recovery


One legacy of the pandemic is the extra support the nation now needs to get healthy, as well as rehabilitation support for long COVID sufferers. Kate Cracknell looks at the early response from the industry with some of the programmes underway
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A new pioneering approach looks to help cancer patients prepare for and respond to treatment by offering them a combination of exercise, nutrition and psychological support. Launched by Sheffield Hallam University’s Advanced Wellbeing Research Centre (AWRC) – and funded by Yorkshire Cancer Research – the new approach will provide tailored support and guidance for each individual in the programme.
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©Cybertrek 2022

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