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PRODUCT NEWS
iS Clinical introduces epigenetic retinol duo: Retinol+ Emulsion
02 Oct 2023 . BY Megan Whitby
The new launch is available in two different strengths; 0.3 per cent or 1 per cent / iS Clinical
The new launch is available in two different strengths; 0.3 per cent or 1 per cent / iS Clinical

Photo: Harpar Grace International
The new Retinol+ Emulsion duo offers a 360-skin overhaul
– Alana Chalmers
Cosmeceutical skincare brand iS Clinical has developed a brand new retinol product designed to optimise the pro-ageing ingredient's benefits while minimising its potential side effects.

Available in two different strengths (0.3 per cent and 1 per cent), Retinol+ Emulsion is powered by two decades of scientific research and has been designed to offer a comprehensive solution to a myriad of skincare concerns.

The star ingredient is a keratolytic form of retinol which is said to aid in the breakdown of excessive and damaged skin cells. When combined with a proprietary blend of bakuchiol, antioxidants and extremozymes, the formula is claimed to help target fine lines, wrinkles, uneven skin tone, rough texture and blemishes.

Moreover, it works to enhance the complexion promoting smoother, softer and brighter-looking skin.

Retinol+ Emulsion is suitable for normal, oily, dry or combination skin types.

Clinically-backed results
Both formulas are backed by scientific research and iS Clinical’s commitment to evidence-based formulas. Subject studies for the 0.3 per cent solution show a 22 per cent reduction of wrinkles, an increase in skin elasticity of 22 per cent and skin hydration up 18 per cent.

In gene activation studies – with a protocol designed to mimic at-home use – both solutions were shown to significantly influence gene expression in the skin.

Differential gene expression was demonstrated for 3,233 genes, positively impacting up-regulating processes including wound healing and skin repair, controlled apoptosis (programmed cell death), antioxidant activity, skin homeostasis and dermal-epidermal junction maintenance.

Alana Chalmers, Harpar Grace International founder and CEO (iS Clinical parent company), says: “ iS Clinical is a brand known for its extensive formulation testing and in-house expertise. The new Retinol+ Emulsion duo offers a 360-skin overhaul, with a fast-acting keratolytic formula, encapsulated and bio-identical lipids, phosphatidylcholine and triglycerides across two strengths.

“We look forward to introducing our key partners to the formula that makes iS Clinical so unique”.

More about iS Clincial
iS Clinical products and treatments are available through a carefully selected network of medical spas, professional aesthetic practitioners, dermatologists, plastic surgeons and doctors.
Supplier details
Harpar Grace International

Harpar Grace International, based in Hampshire in the UK is a privately-owned and entrepreneurial business and has grown and evolved over the last 10 years into one of the aesthetic industry’s leading distributing and brand houses with a team of over 30 and a portfolio of 4 clinically proven brand offerings.
https://harpargrace.com/
More details
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News   Products   Magazine   Subscribe
PRODUCT NEWS
iS Clinical introduces epigenetic retinol duo: Retinol+ Emulsion
02 Oct 2023 . BY Megan Whitby
The new launch is available in two different strengths; 0.3 per cent or 1 per cent / iS Clinical

Photo: Harpar Grace International
The new Retinol+ Emulsion duo offers a 360-skin overhaul
– Alana Chalmers
Cosmeceutical skincare brand iS Clinical has developed a brand new retinol product designed to optimise the pro-ageing ingredient's benefits while minimising its potential side effects.

Available in two different strengths (0.3 per cent and 1 per cent), Retinol+ Emulsion is powered by two decades of scientific research and has been designed to offer a comprehensive solution to a myriad of skincare concerns.

The star ingredient is a keratolytic form of retinol which is said to aid in the breakdown of excessive and damaged skin cells. When combined with a proprietary blend of bakuchiol, antioxidants and extremozymes, the formula is claimed to help target fine lines, wrinkles, uneven skin tone, rough texture and blemishes.

Moreover, it works to enhance the complexion promoting smoother, softer and brighter-looking skin.

Retinol+ Emulsion is suitable for normal, oily, dry or combination skin types.

Clinically-backed results
Both formulas are backed by scientific research and iS Clinical’s commitment to evidence-based formulas. Subject studies for the 0.3 per cent solution show a 22 per cent reduction of wrinkles, an increase in skin elasticity of 22 per cent and skin hydration up 18 per cent.

In gene activation studies – with a protocol designed to mimic at-home use – both solutions were shown to significantly influence gene expression in the skin.

Differential gene expression was demonstrated for 3,233 genes, positively impacting up-regulating processes including wound healing and skin repair, controlled apoptosis (programmed cell death), antioxidant activity, skin homeostasis and dermal-epidermal junction maintenance.

Alana Chalmers, Harpar Grace International founder and CEO (iS Clinical parent company), says: “ iS Clinical is a brand known for its extensive formulation testing and in-house expertise. The new Retinol+ Emulsion duo offers a 360-skin overhaul, with a fast-acting keratolytic formula, encapsulated and bio-identical lipids, phosphatidylcholine and triglycerides across two strengths.

“We look forward to introducing our key partners to the formula that makes iS Clinical so unique”.

More about iS Clincial
iS Clinical products and treatments are available through a carefully selected network of medical spas, professional aesthetic practitioners, dermatologists, plastic surgeons and doctors.
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PRODUCT NEWS
Yon-Ka develops Beard Oil
Yon-Ka has launched its new Beard Oil, to strengthen and soften beard hair without leaving a greasy finish.
Pharmos Natur launches Lunar Skin Ritual using products designed to work at night
Pharmos Natur has launched a Night Elixir and Night Cream to be used in its latest therapy, the Lunar Skin Ritual.
HPO Tech introduces hyperbaric chamber, Oyster
HPO Tech has created a single-seat hyperbaric chamber, called Oyster, with an acrylic domed lid that opens upwards like a shell.
Manduka debuts premium P/ROX hybrid fitness mat
Manduka, a leading manufacturer of premium yoga mats has launched its P/ROX hybrid fitness mat, crafted for athletes and functional fitness practitioners who move between yoga and fitness training.
Rebalance Tech ramps up Impulse rollout
Consumer desire for overall wellbeing is driving demand for Impulse, a multisensory bed by Rebalance Tech, according to distributor Spa Vision.
Nilo Spa Design introduces Marea dry flotation bed
Nilo Spa Design has launched a dry flotation bed called Marea that uses 500 litres of water to support the body evenly in a zero-gravity-like experience.
Esse Skincare upgrades Probiotic Serum with fourth live probiotic species
Microbiome-focused Esse Skincare has upgraded its Probiotic Serum formula with a fourth live probiotic species.
Voya launches Resurge Hair and Scalp Elixir and spa treatments
Organic seaweed spa brand Voya has developed a lightweight scalp serum called Resurge Hair and Scalp Elixir.
Templespa releases brightening Glass Act eye serum
Templespa has developed a memory gel serum called Glass Act that is designed to cool, comfort and revive the delicate skin found around the eyes.
Sweet Bee Organics enters spa market at The Ned London with magnesium-infused treatment
Modern apothecary skincare brand Sweet Bee Organics has entered the spa market with its first treatment at the hotel and members’ club The Ned London, in the UK.
OSKIA unveils Midnight Eye Q cream for nocturnal repair
Nutri-cosmeceutical beauty brand OSKIA has unveiled an eye cream called Midnight Eye Q, which has been designed to regenerate the delicate skin in alignment with the body’s circadian rhythm.
Epicutis launches Hydrobiome Serum and professional-only Massage Oil
Biotechnology-driven skincare company, Epicutis, has launched two new products in its mission to deliver long-term skin health, barrier recovery and microbiome harmony. 
+ More products   
 
COMPANY PROFILES
Seed To Skin

Founded by Jeanette Thottrup in 2018, in Tuscany, Seed to Skin is an award winning skincare line. [more...]
+ More profiles  
CATALOGUE GALLERY
+ More catalogues  

DIRECTORY
+ More directory  
DIARY

 

21-23 Jun 2026

Spa Life International (UK)

Midlands (Venue TBA), Liphook, United Kingdom
26-27 Jun 2026

The Longevity Show

Tobacco Docks, London, United Kingdom
+ More diary  
 


ADVERTISE . CONTACT US

Leisure Media
Tel: +44 (0)1462 431385

©Cybertrek 2026

ABOUT LEISURE MEDIA
LEISURE MEDIA MAGAZINES
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LEISURE MEDIA WEBSITES
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PRINT SUBSCRIPTIONS
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