GET SPA BUSINESS
magazine
Yes! Send me the FREE digital editions of Spa Business and Spa Business insider magazines and the FREE weekly Spa Business and Spa Business insider ezines and breaking news alerts!
Not right now, thanksclose this window
Finishing touch
COVID attacks fat cells

Researchers from Stanford University set out to explain why people with obesity are at higher risk when contracting COVID-19, as Tom Walker reports


New research suggests that COVID-19 infects fat cells, explaining why overweight and obese are at a higher risk of severe illness and death from COVID-19.

The study lends added credibility to the work being done by spa and wellness businesses in supporting people to control their levels of body fat.

The study, led by Stanford University School of Medicine, examined whether fat tissue obtained from bariatric surgery patients could become infected with the SARS-CoV-2, and tracked how various types of cells responded to the virus.

It found that fat cells and also immune cells (macrophages) can be infected, leading to a ‘robust inflammatory response’.

The findings show the virus is able to evade the immune defences within the body’s fat cells, before causing inflammation elsewhere in the body.

In addition to explaining why patients with excess body weight are particularly vulnerable, it may also explain why some younger adults with no underlying health issues become so ill.

‘Permissive’ fat tissue
In reporting the details of the findings, the researchers said: “Collectively, our findings indicate that adipose (fat) tissue supports SARS-CoV-2 infection and pathogenic inflammation and may explain the link between obesity and severe COVID-19.“Obesity is associated with adverse COVID-19 outcomes, but the underlying mechanism was unknown up to this point.

“We demonstrate that human fat tissue is ‘permissive’ to SARS-CoV-2 infection – the virus that causes COVID-19 – and that infection elicits an inflammatory response, including the secretion of known inflammatory mediators of severe COVID-19.

“We identify two cellular targets of SARS-CoV-2 infection in adipose tissue: mature adipocytes and adipose tissue macrophages.

“Adipose tissue macrophage infection is largely restricted to a highly inflammatory subpopulation of macrophages, present at baseline, that is further activated in response to SARS-CoV-2 infection.

“Preadipocytes, while not infected, adopt a pro-inflammatory phenotype. We further demonstrate that SARS-CoV-2 RNA is detectable in adipocytes in COVID-19 autopsy cases and is associated with an inflammatory infiltrate.

The research has not yet been peer-reviewed, but has been published: www.spabusiness.com/fatcells

Sign up here to get the Spa Business and Spa Business insider weekly ezines and every issue of Spa Business and Spa Business insider magazines free on digital.
FEATURED SUPPLIERS

To inspire and inform: ISPA gears up for 2022 conference in Las Vegas
Join ISPA at its 2022 ISPA Conference where the most innovative spa products and services on the market will be showcased for motivated spa buyers from all sectors of the spa industry to explore and access. [more...]

Comfort Zone: Davines Group and Rodale Institute launch a new partnership to sustain regenerative agriculture
The Comfort Zone - Davines Group and Rodale Institute have partnered to create the first International Regenerative Organic Research & Education Center in Parma, Italy. [more...]
+ More featured suppliers  
COMPANY PROFILES
Phytomer

Phytomer remains an independent family business led by the founder’s son, Antoine Gédouin. We coun [more...]
Barr + Wray Ltd

Being able to create award-winning spas, offering a full interior design package and a technical a [more...]
+ More profiles  
CATALOGUE GALLERY
 

+ More catalogues  

VIDEO GALLERY

BluGalaxy a Division of Blu Spas
This animation showcases the beautiful concept design of BluGalaxy Spa. Find out more...
+ More videos  

DIRECTORY
+ More directory  
DIARY

 

01-03 Feb 2022

Spatex 2022

Coventry Building Society Arena, Coventry, United Kingdom
10-14 Mar 2022

Cosmoprof Worldwide Bologna

Fair District, Bologna, Italy
+ More diary  
 
ABOUT LEISURE MEDIA
LEISURE MEDIA MAGAZINES
LEISURE MEDIA HANDBOOKS
LEISURE MEDIA WEBSITES
LEISURE MEDIA PRODUCT SEARCH
 
SPA BUSINESS
SPA OPPORTUNITIES
SPA BUSINESS HANDBOOK
PRINT SUBSCRIPTIONS
FREE DIGITAL SUBSCRIPTIONS
ADVERTISE . CONTACT US

Leisure Media
Tel: +44 (0)1462 431385

©Cybertrek 2022
News   Products   Magazine
Finishing touch
COVID attacks fat cells

Researchers from Stanford University set out to explain why people with obesity are at higher risk when contracting COVID-19, as Tom Walker reports


New research suggests that COVID-19 infects fat cells, explaining why overweight and obese are at a higher risk of severe illness and death from COVID-19.

The study lends added credibility to the work being done by spa and wellness businesses in supporting people to control their levels of body fat.

The study, led by Stanford University School of Medicine, examined whether fat tissue obtained from bariatric surgery patients could become infected with the SARS-CoV-2, and tracked how various types of cells responded to the virus.

It found that fat cells and also immune cells (macrophages) can be infected, leading to a ‘robust inflammatory response’.

The findings show the virus is able to evade the immune defences within the body’s fat cells, before causing inflammation elsewhere in the body.

In addition to explaining why patients with excess body weight are particularly vulnerable, it may also explain why some younger adults with no underlying health issues become so ill.

‘Permissive’ fat tissue
In reporting the details of the findings, the researchers said: “Collectively, our findings indicate that adipose (fat) tissue supports SARS-CoV-2 infection and pathogenic inflammation and may explain the link between obesity and severe COVID-19.“Obesity is associated with adverse COVID-19 outcomes, but the underlying mechanism was unknown up to this point.

“We demonstrate that human fat tissue is ‘permissive’ to SARS-CoV-2 infection – the virus that causes COVID-19 – and that infection elicits an inflammatory response, including the secretion of known inflammatory mediators of severe COVID-19.

“We identify two cellular targets of SARS-CoV-2 infection in adipose tissue: mature adipocytes and adipose tissue macrophages.

“Adipose tissue macrophage infection is largely restricted to a highly inflammatory subpopulation of macrophages, present at baseline, that is further activated in response to SARS-CoV-2 infection.

“Preadipocytes, while not infected, adopt a pro-inflammatory phenotype. We further demonstrate that SARS-CoV-2 RNA is detectable in adipocytes in COVID-19 autopsy cases and is associated with an inflammatory infiltrate.

The research has not yet been peer-reviewed, but has been published: www.spabusiness.com/fatcells

Sign up here to get the Spa Business and Spa Business insider weekly ezines and every issue of Spa Business and Spa Business insider magazines free on digital.
LATEST NEWS
Sweet dreams: Rosewood rolls out Alchemy of Sleep retreats
Rosewood Hotels & Resorts has launched a global sleep retreat collection designed to promote rest through sleep-inducing treatments, movement-driven activities and special amenities.
IHG's first Regent Resort in Vietnam to feature tropical wellness retreat
IHG Hotels & Resorts will launch the first resort from its recently acquired luxury brand, Regent Hotels & Resorts, in South East Asia in Q1 2022.
Healing Summit 2022 postponed to September
Annual industry event The Healing Summit has been rescheduled from May to 3 - 4 September 2022.
Sensei expands leadership team in preparation for new retreat opening 2022
Sensei, the wellness brand owned by tech billionaire Larry Ellison, has appointed Annika Jackson as general manager and Michael Conte as retreat director of the brand’s upcoming second outpost Sensei Porcupine Creek.
Como Shambhala to debut in France with countryside wellness retreat
The Como Group has announced plans to open its first luxury boutique hotel in France in the world-famous wine region of Burgundy.
Vinotherapy and mud rituals inspire Four Seasons Napa Valley spa programming
The new spa at the recently-opened Four Seasons Napa Valley in Calistoga, California, has been inspired by the resort’s onsite vineyard and local Native American healing wisdom.
Soneva's new spa and wellness brand blends ancient and modern healing techniques
Barefoot luxury hotel and wellness brand Soneva has concocted a new spa and wellness concept combining ancient healing wisdom with modern science.
Rancho La Puerta names Luis Arturo Aguilar new spa manager
Luis Arturo Aguilar has been appointed ​the new spa manager at wellness destination and spa Rancho La Puerta in Tecate, Mexico.
B Corp Beauty Coalition launches to redefine industry’s sustainability standards
Twenty-six Certified B Corporations across eight countries and three continents have formed a new coalition seeking to improve the beauty industry and personal care sector’s sustainability standards.
Auberge Resorts opens beachfront Mayan wellness sanctuary on Riviera Maya
Auberge Resorts Collection has opened a brand new oceanfront resort and spa in Kanai, Mexico, a region claimed to be steeped in the lore of the ancient Mayans.
Myzone sets a course for unicorn status as investment from BGF values the brand at US$102m
Myzone has secured a US$17.2m worth of investment from growth capital investor BGF – a move that values the brand at US$102m. The deal is all equity-based.
Longevity is the next disruptor says Michael Roizen – 90 will be the new 40
The Cleveland Clinic’s chief wellness officer Michael Roizen predicts longevity will become the next major disruptor, according to his recent interview with Spa Business.
+ More news   
 
FEATURED SUPPLIERS

To inspire and inform: ISPA gears up for 2022 conference in Las Vegas
Join ISPA at its 2022 ISPA Conference where the most innovative spa products and services on the market will be showcased for motivated spa buyers from all sectors of the spa industry to explore and access. [more...]

Comfort Zone: Davines Group and Rodale Institute launch a new partnership to sustain regenerative agriculture
The Comfort Zone - Davines Group and Rodale Institute have partnered to create the first International Regenerative Organic Research & Education Center in Parma, Italy. [more...]
+ More featured suppliers  
COMPANY PROFILES
Phytomer

Phytomer remains an independent family business led by the founder’s son, Antoine Gédouin. We coun [more...]
+ More profiles  
CATALOGUE GALLERY
+ More catalogues  

VIDEO GALLERY

BluGalaxy a Division of Blu Spas
This animation showcases the beautiful concept design of BluGalaxy Spa. Find out more...
+ More videos  

DIRECTORY
+ More directory  
DIARY

 

01-03 Feb 2022

Spatex 2022

Coventry Building Society Arena, Coventry, United Kingdom
10-14 Mar 2022

Cosmoprof Worldwide Bologna

Fair District, Bologna, Italy
+ More diary  
 


ADVERTISE . CONTACT US

Leisure Media
Tel: +44 (0)1462 431385

©Cybertrek 2022

ABOUT LEISURE MEDIA
LEISURE MEDIA MAGAZINES
LEISURE MEDIA HANDBOOKS
LEISURE MEDIA WEBSITES
LEISURE MEDIA PRODUCT SEARCH
PRINT SUBSCRIPTIONS
FREE DIGITAL SUBSCRIPTIONS