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Daily yoga and meditation were part of the wellness intervention plans / photo: shutterstock/bikeriderlondon
Since it was first discovered more than 100 years ago, Alzheimer’s disease has been without an effective treatment. Worldwide, nearly 44 million people are believed to be living with the brain disorder or other forms of dementia. By 2030 this could rise to nearly 76 million according to the US-based BrightFocus Foundation.
But the outlook may not be so bleak if the findings of a small US pilot study are anything to go by. Scientists at the Buck Institute for Research on Aging and the University of California, Los Angeles have discovered that lifestyle and wellness interventions have reversed memory loss in patients with Alzheimer’s disease for the first time. Although the results are anecdotal, the findings are “very encouraging” says study author and neurology professor Dr Dale Bredesen.
Individualised intervention As part of the trial, a group of experts put together a 36-point plan for 10 patients with Alzheimer’s. The plans included taking up yoga and meditation twice a day to reduce stress, exercise and getting an optimal seven to eight hours of sleep. They also comprised strict diet changes, including fasting (see SB14/4 p50).
Each plan was personalised, based on extensive testing to determine what was affecting brain signals in each patient. Although the programmes were difficult to follow – none of the participants were able to fully adhere to them – Bredesen believes a multiple-component approach is key. “The existing Alzheimer’s drug affects a single target, but the disease is more complex,” he says. “Imagine having a roof with 36 holes, and your drug patched one very well... You’d still have 35 other leaks, and so the underlying process may not be affected much.”
Promising results The results were promising, with nine out of the 10 patients seeing advancements in three to six months. The only patient not to benefit had late-stage Alzheimer’s.
Such were the improvements that six participants, who’d been struggling at work or had to stop because of cognitive issues, were able to return to their jobs. Meanwhile, those who stayed in employment showed increased performance. Bredesen adds: “It’s noteworthy that the major side effect of this therapeutic system are improved health and body mass index: a stark contrast to the side effects of many drugs.”
Further research Overall, the results suggest that memory loss may be reversed, and improvements sustained, by following a tailored therapeutic plan. Yet Bredesen cautions that further research is needed. “The current, anecdotal results require a larger trial, not only to confirm or refute the results reported here, but also to address key questions raised, such as the degree of improvement that can be achieved routinely, how late in the course of cognitive decline reversal can be effected... and how long improvement can be sustained,” he says.
Read more from this issue of Spa Business magazine
View contents of Spa Business 2015 issue 1
Letters: Letters
We need sales people in spas says consultant Helen Merchant
Interview -Rich Weissmann: Rich Weissmann
Weissmann, a partner at private equity firm KSL, talks spa investment with Rhianon Howells and reveals its plans for the Miraval brand
Wellness: All in the mind
Twin Peaks director David Lynch has a foundation which uses meditation to help those facing extreme trauma and stress. Julie Cramer talks to the foundation’s co-founder Bob Roth
How could spas adapt their design and services to help people with cognitive impairments? We cover this in our feature focused on age-friendly facilities on page 64
In the fast-paced world of fitness and wellness, where high-intensity workouts push us to
our limits and the sweat pours, the importance of efficient recovery cannot be overstated. [more...]
+ More featured suppliers
COMPANY PROFILES
Starpool SRL
Founded in 1975 in the Italian Dolomites, Starpool is a company specialising in wellness, health and [more...]
Borghese Roma
Borghese is an Italian luxury skincare brand founded in 1957 by Princess Marcella Borghese. [more...]
Daily yoga and meditation were part of the wellness intervention plans / photo: shutterstock/bikeriderlondon
Since it was first discovered more than 100 years ago, Alzheimer’s disease has been without an effective treatment. Worldwide, nearly 44 million people are believed to be living with the brain disorder or other forms of dementia. By 2030 this could rise to nearly 76 million according to the US-based BrightFocus Foundation.
But the outlook may not be so bleak if the findings of a small US pilot study are anything to go by. Scientists at the Buck Institute for Research on Aging and the University of California, Los Angeles have discovered that lifestyle and wellness interventions have reversed memory loss in patients with Alzheimer’s disease for the first time. Although the results are anecdotal, the findings are “very encouraging” says study author and neurology professor Dr Dale Bredesen.
Individualised intervention As part of the trial, a group of experts put together a 36-point plan for 10 patients with Alzheimer’s. The plans included taking up yoga and meditation twice a day to reduce stress, exercise and getting an optimal seven to eight hours of sleep. They also comprised strict diet changes, including fasting (see SB14/4 p50).
Each plan was personalised, based on extensive testing to determine what was affecting brain signals in each patient. Although the programmes were difficult to follow – none of the participants were able to fully adhere to them – Bredesen believes a multiple-component approach is key. “The existing Alzheimer’s drug affects a single target, but the disease is more complex,” he says. “Imagine having a roof with 36 holes, and your drug patched one very well... You’d still have 35 other leaks, and so the underlying process may not be affected much.”
Promising results The results were promising, with nine out of the 10 patients seeing advancements in three to six months. The only patient not to benefit had late-stage Alzheimer’s.
Such were the improvements that six participants, who’d been struggling at work or had to stop because of cognitive issues, were able to return to their jobs. Meanwhile, those who stayed in employment showed increased performance. Bredesen adds: “It’s noteworthy that the major side effect of this therapeutic system are improved health and body mass index: a stark contrast to the side effects of many drugs.”
Further research Overall, the results suggest that memory loss may be reversed, and improvements sustained, by following a tailored therapeutic plan. Yet Bredesen cautions that further research is needed. “The current, anecdotal results require a larger trial, not only to confirm or refute the results reported here, but also to address key questions raised, such as the degree of improvement that can be achieved routinely, how late in the course of cognitive decline reversal can be effected... and how long improvement can be sustained,” he says.
Read more from this issue of Spa Business magazine
View contents of Spa Business 2015 issue 1
Letters: Letters
We need sales people in spas says consultant Helen Merchant
Interview -Rich Weissmann: Rich Weissmann
Weissmann, a partner at private equity firm KSL, talks spa investment with Rhianon Howells and reveals its plans for the Miraval brand
Wellness: All in the mind
Twin Peaks director David Lynch has a foundation which uses meditation to help those facing extreme trauma and stress. Julie Cramer talks to the foundation’s co-founder Bob Roth
How could spas adapt their design and services to help people with cognitive impairments? We cover this in our feature focused on age-friendly facilities on page 64
Manipulating the gut microbiome could become a powerful tool for preserving brain health and
resilience as people age, according to research led by Professor Paola Tognini, a neuroscientist
at the Sant'Anna School of Advanced Studies in Pisa, Italy.
Jessica Sloyan, a wellness operations and training expert, has established an independent
private training academy to provide professional qualifications for practitioners looking to offer
immersive wellness experiences.
The International Spa Association (ISPA) has published its full 2026 US Spa Industry Study,
providing further insights into the region’s total US$1 billion (€855 million, £780 million)
industry revenue increase from 2024 to 2025.
Ameyalli, the 78-acre wellbeing resort and residential community in Midway in Utah, US, has
broken ground on phase two of the hot spring development – the Ameyalli Resort and Spa –
which is due to open in 2028.
TLee Spas and Wellness has revealed the design concept for a high-tech spa with body
mapping scanners to improve public health, for AI company Midjourney.
Gran Hotel Taoro in northern Tenerife, Spain, has completed the final phase of its three-year
renovation with the debut of its Sandára Wellness Centre.
Hand and Stone Massage and Facial Spa, the spa business with more than 650 locations across
the US and Canada, has appointed franchise expert Carrie Walsh as CEO as the company plans
to expand.
Synergy – The Retreat Show, the global trade show for retreats, has launched a global research
initiative that will provide insights into the retreat sector from both consumer and industry
perspectives.
The Wellness Tourism Association (WTA) has published a non-regulatory global industry
framework designed to ensure the retreat market offers responsible experiences.
In the fast-paced world of fitness and wellness, where high-intensity workouts push us to
our limits and the sweat pours, the importance of efficient recovery cannot be overstated. [more...]
+ More featured suppliers
COMPANY PROFILES
Starpool SRL Founded in 1975 in the Italian Dolomites, Starpool is a company specialising in wellness, health and [more...]
