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PROMOTION
Innovative studies on cell senescence inspire Comfort Zone’s new approach to anti-ageing
21 Dec 2021
A dermatologist helped to develop the Sublime Skin range /
A dermatologist helped to develop the Sublime Skin range
With the relaunch of Sublime Skin, the Comfort Zone R&R team has further deepened its knowledge of skin ageing mechanisms in order to offer even more complete and effective cosmetic solutions.

The innovation relates to the study and treatment of cellular senescence, a critical phenomenon that accompanies skin ageing and affects all cells and all skin layers, globally and progressively compromising skin vitality and functionality.

Research has found that when cells age and reach the senescence stage, they don’t simply stop stimulating growth factors. Instead, they also release harmful substances, known as SASPs (senescence-associated secretory phenotypes), inflammatory molecules that attack neighbouring cells, causing them to enter a state of premature senescence.

This triggers a chain reaction in the skin’s layers that causes and aggravates wrinkles, dryness and a visible loss of tone.

More specifically, inflammatory molecules (SASPs) in the epidermis alter the turnover causing weakening of the barrier function and a greater water loss.

In the dermis, they compromise the fibroblasts, reducing collagen and elastin production and they cause an increase in metalloproteinases, the enzymes that degrade collagen and elastin, damaging the skin, which becomes less firm and elastic.

In the hypodermis the secretion of inflammatory SASP molecules also reduces adipogenesis, leading to less lipid accumulation, which explains the loss of tissue volume observed with age.

In order to counteract cellular senescence, Comfort Zone has selected Acetyl Hexapeptide-8 for the new Sublime Skin Intensive Serum.

This high tech ingredient reduces the presence of SASPs by 55 per cent and therefore weakens the degeneration caused by senescent cells. Furthermore, the compound blocks the skin neurotransmitter responsible for facial expression, inhibiting muscle contraction and reducing wrinkles and expression lines.

To learn more, head to Comfort Zone’s official website.
Comfort Zone
Address: Via Don Angelo Calzolari 55/A
43126 Parma Italy

UK Office:
14 Gray’s Inn Road, London
WC1X 8HN United Kingdom
T. +44 20 3301 0496
Company profile

Comfort Zone

Comfort Zone’s comprehensive face and body professional and retail range allows clients to experience personalised facials and memorable rituals enhanced by signature massages and high-tech devices.

Read Comfort Zone's full profile here
Supplier details
Comfort Zone

Parma Italy
Conceived in 1996 by Dr Davide Bollati, founder of the Davines Group, a leading Italian certified B Corporation developing and manufacturing sustainable skin and hair care, Comfort Zone offers result-oriented face and body products and professional treatments.
https://www.comfortzoneskin.com/
More details
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Uniting the world of spa & wellness
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News   Products   Magazine   Subscribe
PROMOTION
Innovative studies on cell senescence inspire Comfort Zone’s new approach to anti-ageing
21 Dec 2021
A dermatologist helped to develop the Sublime Skin range
With the relaunch of Sublime Skin, the Comfort Zone R&R team has further deepened its knowledge of skin ageing mechanisms in order to offer even more complete and effective cosmetic solutions.

The innovation relates to the study and treatment of cellular senescence, a critical phenomenon that accompanies skin ageing and affects all cells and all skin layers, globally and progressively compromising skin vitality and functionality.

Research has found that when cells age and reach the senescence stage, they don’t simply stop stimulating growth factors. Instead, they also release harmful substances, known as SASPs (senescence-associated secretory phenotypes), inflammatory molecules that attack neighbouring cells, causing them to enter a state of premature senescence.

This triggers a chain reaction in the skin’s layers that causes and aggravates wrinkles, dryness and a visible loss of tone.

More specifically, inflammatory molecules (SASPs) in the epidermis alter the turnover causing weakening of the barrier function and a greater water loss.

In the dermis, they compromise the fibroblasts, reducing collagen and elastin production and they cause an increase in metalloproteinases, the enzymes that degrade collagen and elastin, damaging the skin, which becomes less firm and elastic.

In the hypodermis the secretion of inflammatory SASP molecules also reduces adipogenesis, leading to less lipid accumulation, which explains the loss of tissue volume observed with age.

In order to counteract cellular senescence, Comfort Zone has selected Acetyl Hexapeptide-8 for the new Sublime Skin Intensive Serum.

This high tech ingredient reduces the presence of SASPs by 55 per cent and therefore weakens the degeneration caused by senescent cells. Furthermore, the compound blocks the skin neurotransmitter responsible for facial expression, inhibiting muscle contraction and reducing wrinkles and expression lines.

To learn more, head to Comfort Zone’s official website.
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Comfort Zone
Address: Via Don Angelo Calzolari 55/A
43126 Parma Italy

UK Office:
14 Gray’s Inn Road, London
WC1X 8HN United Kingdom
T. +44 20 3301 0496
PRODUCT NEWS
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Spa uniform specialist Fashionizer Spa has launched a new line of tunics and trousers called the Grove Collection.
Earthlite LLC announces parent operating group Intentional Wellness Brands
Earthlite LLC has announced the formation of a parent operating group, Intentional Wellness Brands (IWB), which comprises a portfolio of wellness companies.
Yon-Ka develops Beard Oil
Yon-Ka has launched its new Beard Oil, to strengthen and soften beard hair without leaving a greasy finish.
Pharmos Natur launches Lunar Skin Ritual using products designed to work at night
Pharmos Natur has launched a Night Elixir and Night Cream to be used in its latest therapy, the Lunar Skin Ritual.
HPO Tech introduces hyperbaric chamber, Oyster
HPO Tech has created a single-seat hyperbaric chamber, called Oyster, with an acrylic domed lid that opens upwards like a shell.
Manduka debuts premium P/ROX hybrid fitness mat
Manduka, a leading manufacturer of premium yoga mats has launched its P/ROX hybrid fitness mat, crafted for athletes and functional fitness practitioners who move between yoga and fitness training.
Rebalance Tech ramps up Impulse rollout
Consumer desire for overall wellbeing is driving demand for Impulse, a multisensory bed by Rebalance Tech, according to distributor Spa Vision.
Nilo Spa Design introduces Marea dry flotation bed
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Esse Skincare upgrades Probiotic Serum with fourth live probiotic species
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Tobacco Docks, London, United Kingdom
03-05 Jul 2026

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Copenhagen, Copenhagen, Denmark
+ More diary  
 


ADVERTISE . CONTACT US

Leisure Media
Tel: +44 (0)1462 431385

©Cybertrek 2026

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