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A new anti-senescence serum from Biologique Recherche offers transformative results and raises the bar in anti-ageing skincare when combined with its iconic collagen formula
Sérum Progeskin’s formula combats signs of ageing / photo: Biologique Recherche
After nearly 50 years, Biologique Recherche has solidified its reputation for premium, high-performance skincare with its unique, clinical approach that consistently delivers both immediate and enduring results.
The latest innovation from the leading French skincare authority – Sérum Progeskin – represents the forefront of skin biology expertise, addressing one of the primary causes of skin ageing: cellular senescence.
Innovative defense Derived from the Latin “senescene” meaning ‘to grow old’, cellular senescence is a state where cells cease to divide but remain metabolically active. This process accelerates with natural ageing. Typically, cellular senescence occurs in response to damage, allowing tissue regeneration and the removal of dead cells. However, in ageing, damage often surpasses the repair capacity, leading to an accumulation of senescent cells.
These cells contribute to a pro-inflammatory environment that fosters age-related diseases and visible signs of ageing, such as thinning skin, flattened dermal-epidermal junctions, wrinkles, reduced elasticity and pigmentation issues.
The R&D teams at Biologique Recherche have focused on two key proteins involved in this process, firstly, Progerin, a protein that accumulates with age, disrupting cell regeneration, extracellular matrix integrity and inflammatory responses. This leads to thinning skin, wrinkles and loss of subcutaneous fat, resulting in a gaunt appearance typical of chronological ageing and secondly, Klotho. This is known as the ‘youth protein’ and maintains proper cell function by enhancing skin resistance to oxidative stress and blocking ageing pathways. Unlike progerin, klotho supports skin health and delays cell senescence.
Sérum Progeskin’s formula targets these proteins to combat ageing. Designed to be used around the face, neck and décolleté, it leaves the skin firmer, plumper and more toned, visibly reducing wrinkles and fine lines for a rejuvenated appearance.
Sérum Progeskin features a cutting-edge blend of two active ingredients: Progescence, which decreases progerin synthesis, reducing senescent cell accumulation over time and Pro-KL which activates klotho protein, supporting cellular metabolism and promoting skin cell longevity.
Potent partners For enhanced anti-ageing results, Biologique Recherche has paired Sérum Progeskin with its renowned Sérum Collagène Originel. This powerful combination addresses established wrinkles and preserves youthful skin.
Launched in 2022, Sérum Collagène Originel targets four primary types of collagen using Type 0 Collagen, silene extract, green microalgae, and soy glycopeptides. Type 0 Collagen, derived from marine jellyfish, is the purest form of collagen, representing the original protein in its raw state.
Working with a marine biotech specialist, Biologique Recherche’s R&D team extracted this ancient collagen to re-densify skin, making it tighter, smoother and plumper, while significantly reducing wrinkle length.
Sérum Collagène Originel specifically addresses established wrinkles, while Sérum Progeskin targets cutaneous ageing. Together, they provide a potent anti-ageing skincare solution.
Dr Philippe Allouche, co-chair and head of creation and R&D at Biologique Recherche, comments: “Sérum Progeskin and Sérum Collagène Originel work in synergy to preserve the skin’s natural youthfulness, delivering a firm and radiant complexion.”
About Biologique Recherche The science-led brand formulates its products without artificial fragrances in its own laboratory in France. Biologique Recherche is the partner of choice for exceptional spas, medical spas and premier luxury hotels in over 80 countries. Biologique Recherche has its own flagship Ambassades in Paris, Rome, Brussels, Stockholm, Shanghai and Los Angeles.
Progescence® and Pro-KL® are trademarks of Biologique Recherche
photo: Biologique Recherche
"Sérum Progeskin and Sérum Collagène Originel work in synergy to preserve the skin’s natural youthfulness" – Dr Philippe Allouche, Biologique Recherche
Read more from this issue of Spa Business magazine
View contents of Spa Business 2024 issue 3
Editor's letter: At a crossroads
As the UK prepares to host this year's Global Wellness Summit, fresh research shows its wellness industry must address a number of issues if it's to maintain levels of unprecedented growth
Spa People: Charlotte Church
The Welsh singer talks about how growing up in the media spotlight has influenced The Dreaming, her healing retreat business
Spa People: Julia Bradbury
Leading a series of Walk Yourself Happy retreats based on her best-selling book and years of TV presenting
Spa People: Samantha Dunn
Shaking up the industry with her new, affordable DIY consultancy programme for entrepreneurs
News report: Big spenders
Finn Partners’ latest research shows how China’s high-net-worth women are redefining luxury travel
News report: Step back in time
Two new GWI reports analyse the growth of the global spa and hot springs markets over the past 10 to 15 years
Interview: Dillip Rajakarier
Following a 450 per cent increase in core revenues, Minor Hotels is planning 200 more properties. Megan Whitby sits down with its CEO
New opening: Kintsugi Space
Patrizia Bortolin talks to Lisa Starr about creating a transformative women-only sanctuary in Abu Dhabi
Research: To inform and inspire
The UK Spa Association has conducted its first survey of spa businesses in the country for 18 years. GM Bobby Griffiths unveils the numbers
Research: From wellness to wellbeing
A new study uncovers four wellness consumer market segments ripe for innovation. WELLSurvey co-author Kevin Kelly reveals the findings in a Spa Business exclusive
First person: To the source
Jane Kitchen takes to the sulphurous waters of Terme di Saturnia in Italy and shares details about its exciting upcoming sister site in Milan
Promotion: L'OCCITANE en Provence – the art of recovery
With an approach to wellbeing that’s both holistic and grounded in science, the latest massage from L’OCCITANE en Provence promises to have a powerfully-beneficial effect on customers, both in the spa and at home
New opening: Surrenne at The Emory
The £15k memberships at this wellness club in London sold out in just weeks. Creator Inge Theron tells us why
First person: Playful wellness
A Stella McCartney facial and Tracy Anderson studio are just two USPs Megan Whitby finds at Surrenne
Promotion: TechnoAlpin – naturally cool design
TechnoAlpin’s snow technology is not only an effective way to introduce gentle cold therapy into the spa environment, it’s also a powerful biophilic design element that can bring the wonder of nature indoors
Promotion: Biologique Recherche – potent partnership
A new anti-senescence serum from Biologique Recherche offers transformative results and raises the bar in anti-ageing skincare when combined with its iconic collagen formula
Promotion: Comfort Zone – A longer life for skin
Created to combat the visible signs of ageing, Comfort Zone’s latest range revamp is based on the company’s pioneering research into cutaneous cellular longevity
Promotion: G.M. COLLIN – Clinical excellence in skincare
With laboratories based in Montreal, G.M. Collin’s highly researched derma-corrective treatments have been helping skincare professionals deliver exceptional and exclusive results worldwide for many decades. We talk to VP Myriam Sayer
The Spa Life UK Convention returns from 21–23 June 2026 at Whittlebury Park Hotel, Spa &
Golf Resort, bringing together spa managers, directors and owners for two days of focused
education, meaningful connection and commercial insight. [more...]
A new anti-senescence serum from Biologique Recherche offers transformative results and raises the bar in anti-ageing skincare when combined with its iconic collagen formula
Sérum Progeskin’s formula combats signs of ageing / photo: Biologique Recherche
After nearly 50 years, Biologique Recherche has solidified its reputation for premium, high-performance skincare with its unique, clinical approach that consistently delivers both immediate and enduring results.
The latest innovation from the leading French skincare authority – Sérum Progeskin – represents the forefront of skin biology expertise, addressing one of the primary causes of skin ageing: cellular senescence.
Innovative defense Derived from the Latin “senescene” meaning ‘to grow old’, cellular senescence is a state where cells cease to divide but remain metabolically active. This process accelerates with natural ageing. Typically, cellular senescence occurs in response to damage, allowing tissue regeneration and the removal of dead cells. However, in ageing, damage often surpasses the repair capacity, leading to an accumulation of senescent cells.
These cells contribute to a pro-inflammatory environment that fosters age-related diseases and visible signs of ageing, such as thinning skin, flattened dermal-epidermal junctions, wrinkles, reduced elasticity and pigmentation issues.
The R&D teams at Biologique Recherche have focused on two key proteins involved in this process, firstly, Progerin, a protein that accumulates with age, disrupting cell regeneration, extracellular matrix integrity and inflammatory responses. This leads to thinning skin, wrinkles and loss of subcutaneous fat, resulting in a gaunt appearance typical of chronological ageing and secondly, Klotho. This is known as the ‘youth protein’ and maintains proper cell function by enhancing skin resistance to oxidative stress and blocking ageing pathways. Unlike progerin, klotho supports skin health and delays cell senescence.
Sérum Progeskin’s formula targets these proteins to combat ageing. Designed to be used around the face, neck and décolleté, it leaves the skin firmer, plumper and more toned, visibly reducing wrinkles and fine lines for a rejuvenated appearance.
Sérum Progeskin features a cutting-edge blend of two active ingredients: Progescence, which decreases progerin synthesis, reducing senescent cell accumulation over time and Pro-KL which activates klotho protein, supporting cellular metabolism and promoting skin cell longevity.
Potent partners For enhanced anti-ageing results, Biologique Recherche has paired Sérum Progeskin with its renowned Sérum Collagène Originel. This powerful combination addresses established wrinkles and preserves youthful skin.
Launched in 2022, Sérum Collagène Originel targets four primary types of collagen using Type 0 Collagen, silene extract, green microalgae, and soy glycopeptides. Type 0 Collagen, derived from marine jellyfish, is the purest form of collagen, representing the original protein in its raw state.
Working with a marine biotech specialist, Biologique Recherche’s R&D team extracted this ancient collagen to re-densify skin, making it tighter, smoother and plumper, while significantly reducing wrinkle length.
Sérum Collagène Originel specifically addresses established wrinkles, while Sérum Progeskin targets cutaneous ageing. Together, they provide a potent anti-ageing skincare solution.
Dr Philippe Allouche, co-chair and head of creation and R&D at Biologique Recherche, comments: “Sérum Progeskin and Sérum Collagène Originel work in synergy to preserve the skin’s natural youthfulness, delivering a firm and radiant complexion.”
About Biologique Recherche The science-led brand formulates its products without artificial fragrances in its own laboratory in France. Biologique Recherche is the partner of choice for exceptional spas, medical spas and premier luxury hotels in over 80 countries. Biologique Recherche has its own flagship Ambassades in Paris, Rome, Brussels, Stockholm, Shanghai and Los Angeles.
Progescence® and Pro-KL® are trademarks of Biologique Recherche
photo: Biologique Recherche
"Sérum Progeskin and Sérum Collagène Originel work in synergy to preserve the skin’s natural youthfulness" – Dr Philippe Allouche, Biologique Recherche
Read more from this issue of Spa Business magazine
View contents of Spa Business 2024 issue 3
Editor's letter: At a crossroads
As the UK prepares to host this year's Global Wellness Summit, fresh research shows its wellness industry must address a number of issues if it's to maintain levels of unprecedented growth
Spa People: Charlotte Church
The Welsh singer talks about how growing up in the media spotlight has influenced The Dreaming, her healing retreat business
Spa People: Julia Bradbury
Leading a series of Walk Yourself Happy retreats based on her best-selling book and years of TV presenting
Spa People: Samantha Dunn
Shaking up the industry with her new, affordable DIY consultancy programme for entrepreneurs
News report: Big spenders
Finn Partners’ latest research shows how China’s high-net-worth women are redefining luxury travel
News report: Step back in time
Two new GWI reports analyse the growth of the global spa and hot springs markets over the past 10 to 15 years
Interview: Dillip Rajakarier
Following a 450 per cent increase in core revenues, Minor Hotels is planning 200 more properties. Megan Whitby sits down with its CEO
New opening: Kintsugi Space
Patrizia Bortolin talks to Lisa Starr about creating a transformative women-only sanctuary in Abu Dhabi
Research: To inform and inspire
The UK Spa Association has conducted its first survey of spa businesses in the country for 18 years. GM Bobby Griffiths unveils the numbers
Research: From wellness to wellbeing
A new study uncovers four wellness consumer market segments ripe for innovation. WELLSurvey co-author Kevin Kelly reveals the findings in a Spa Business exclusive
First person: To the source
Jane Kitchen takes to the sulphurous waters of Terme di Saturnia in Italy and shares details about its exciting upcoming sister site in Milan
Promotion: L'OCCITANE en Provence – the art of recovery
With an approach to wellbeing that’s both holistic and grounded in science, the latest massage from L’OCCITANE en Provence promises to have a powerfully-beneficial effect on customers, both in the spa and at home
New opening: Surrenne at The Emory
The £15k memberships at this wellness club in London sold out in just weeks. Creator Inge Theron tells us why
First person: Playful wellness
A Stella McCartney facial and Tracy Anderson studio are just two USPs Megan Whitby finds at Surrenne
Promotion: TechnoAlpin – naturally cool design
TechnoAlpin’s snow technology is not only an effective way to introduce gentle cold therapy into the spa environment, it’s also a powerful biophilic design element that can bring the wonder of nature indoors
Promotion: Biologique Recherche – potent partnership
A new anti-senescence serum from Biologique Recherche offers transformative results and raises the bar in anti-ageing skincare when combined with its iconic collagen formula
Promotion: Comfort Zone – A longer life for skin
Created to combat the visible signs of ageing, Comfort Zone’s latest range revamp is based on the company’s pioneering research into cutaneous cellular longevity
Promotion: G.M. COLLIN – Clinical excellence in skincare
With laboratories based in Montreal, G.M. Collin’s highly researched derma-corrective treatments have been helping skincare professionals deliver exceptional and exclusive results worldwide for many decades. We talk to VP Myriam Sayer
A recent survey by the UK Spa Association (UKSA) into the industry’s approach to cancer care
has revealed that almost half of participating respondents (46 per cent) are unaware that
cancer is a disability and guests with a cancer diagnosis must be given
Mexican operator, Solmar Hotels and Resorts, is hosting a series of events in celebration of
Global Wellness Day, including a Temazcal ceremony at its Playa Grande Resort and Spa in Los
Cabos.
Mandarin Oriental has announced a standalone residence brand, Mansions, which will debut at
Emirates Palace, Mandarin Oriental Mansions, Abu Dhabi, in 2029.
Four Seasons Resort The Nam Hai in Hoi An, Vietnam, has put together a Global Wellness Day
(GWD) agenda with activations rooted in nature and shaped by four pillars of Joy – in
alignment with the day’s theme #JoyMagenta.
The Global Wellness Summit (GWS) will celebrate its 20th anniversary at the 2026 event in
Phuket, Thailand, later this year with the theme: The Science, Art and Soul of Wellness.
Auko, an all-inclusive development, is opening in Phong Nha in Vietnam in Q3 2026, with a
series of 30 tented eco-lodges and wellness hospitality operations by Lumina Wellbeing.
Therme Manchester’s 28-acre development, which will include interconnected glass pavilions
that measure 65,000sq m, will be the largest bathing and wellbeing attraction in the world once
complete, according to prof David Russell, CEO of Therme UK.
Naples Beach Club, a Four Seasons Resort, has opened a 2,800sq m spa called The Sanctuary,
with the design and concept inspired by the Native American people that populated Florida’s
Southwest coast – the Calusa.
Swire Hotels’ luxury hospitality brand Upper House has revealed it will roll out its two-day
House of Healing retreats at its three hotels in Hong Kong, Chengdu and Shanghai.
The Spa Life UK Convention returns from 21–23 June 2026 at Whittlebury Park Hotel, Spa &
Golf Resort, bringing together spa managers, directors and owners for two days of focused
education, meaningful connection and commercial insight. [more...]
