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Biologique Recherche – potent partnership

A new anti-senescence serum from Biologique Recherche offers transformative results and raises the bar in anti-ageing skincare when combined with its iconic collagen formula


After nearly 50 years, Biologique Recherche has solidified its reputation for premium, high-performance skincare with its unique, clinical approach that consistently delivers both immediate and enduring results.

The latest innovation from the leading French skincare authority – Sérum Progeskin – represents the forefront of skin biology expertise, addressing one of the primary causes of skin ageing: cellular senescence.

Innovative defense
Derived from the Latin “senescene” meaning ‘to grow old’, cellular senescence is a state where cells cease to divide but remain metabolically active. This process accelerates with natural ageing.
Typically, cellular senescence occurs in response to damage, allowing tissue regeneration and the removal of dead cells. However, in ageing, damage often surpasses the repair capacity, leading to an accumulation of senescent cells.

These cells contribute to a pro-inflammatory environment that fosters age-related diseases and visible signs of ageing, such as thinning skin, flattened dermal-epidermal junctions, wrinkles, reduced elasticity and pigmentation issues.

The R&D teams at Biologique Recherche have focused on two key proteins involved in this process, firstly, Progerin, a protein that accumulates with age, disrupting cell regeneration, extracellular matrix integrity and inflammatory responses. This leads to thinning skin, wrinkles and loss of subcutaneous fat, resulting in a gaunt appearance typical of chronological ageing and secondly, Klotho. This is known as the ‘youth protein’ and maintains proper cell function by enhancing skin resistance to oxidative stress and blocking ageing pathways. Unlike progerin, klotho supports skin health and delays cell senescence.

Sérum Progeskin’s formula targets these proteins to combat ageing. Designed to be used around the face, neck and décolleté, it leaves the skin firmer, plumper and more toned, visibly reducing wrinkles and fine lines for a rejuvenated appearance.

Sérum Progeskin features a cutting-edge blend of two active ingredients: Progescence, which decreases progerin synthesis, reducing senescent cell accumulation over time and Pro-KL which activates klotho protein, supporting cellular metabolism and promoting skin cell longevity.

Potent partners
For enhanced anti-ageing results, Biologique Recherche has paired Sérum Progeskin with its renowned Sérum Collagène Originel. This powerful combination addresses established wrinkles and preserves youthful skin.

Launched in 2022, Sérum Collagène Originel targets four primary types of collagen using Type 0 Collagen, silene extract, green microalgae, and soy glycopeptides. Type 0 Collagen, derived from marine jellyfish, is the purest form of collagen, representing the original protein in its raw state.

Working with a marine biotech specialist, Biologique Recherche’s R&D team extracted this ancient collagen to re-densify skin, making it tighter, smoother and plumper, while significantly reducing wrinkle length.

Sérum Collagène Originel specifically addresses established wrinkles, while Sérum Progeskin targets cutaneous ageing. Together, they provide a potent anti-ageing skincare solution.

Dr Philippe Allouche, co-chair and head of creation and R&D at Biologique Recherche, comments: “Sérum Progeskin and Sérum Collagène Originel work in synergy to preserve the skin’s natural youthfulness, delivering a firm and radiant complexion.”

About Biologique Recherche
The science-led brand formulates its products without artificial fragrances in its own laboratory in France. Biologique Recherche is the partner of choice for exceptional spas, medical spas and premier luxury hotels in over 80 countries. Biologique Recherche has its own flagship Ambassades in Paris, Rome, Brussels, Stockholm, Shanghai and Los Angeles.

More: www.biologique-recherche.com/en-gb

Progescence® and Pro-KL® are trademarks of Biologique Recherche
photo: Biologique Recherche

"Sérum Progeskin and Sérum Collagène Originel work in synergy to preserve the skin’s natural youthfulness" – Dr Philippe Allouche, Biologique Recherche

Read more from this issue of Spa Business magazine

View contents of Spa Business 2024 issue 3
The new formula is applied to the face, neck and décolleté
The new formula is applied to the face, neck and décolleté / photo: Biologique Recherche
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Uniting the world of spa & wellness
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News   Products   Magazine   Subscribe
Promotion
Biologique Recherche – potent partnership

A new anti-senescence serum from Biologique Recherche offers transformative results and raises the bar in anti-ageing skincare when combined with its iconic collagen formula


After nearly 50 years, Biologique Recherche has solidified its reputation for premium, high-performance skincare with its unique, clinical approach that consistently delivers both immediate and enduring results.

The latest innovation from the leading French skincare authority – Sérum Progeskin – represents the forefront of skin biology expertise, addressing one of the primary causes of skin ageing: cellular senescence.

Innovative defense
Derived from the Latin “senescene” meaning ‘to grow old’, cellular senescence is a state where cells cease to divide but remain metabolically active. This process accelerates with natural ageing.
Typically, cellular senescence occurs in response to damage, allowing tissue regeneration and the removal of dead cells. However, in ageing, damage often surpasses the repair capacity, leading to an accumulation of senescent cells.

These cells contribute to a pro-inflammatory environment that fosters age-related diseases and visible signs of ageing, such as thinning skin, flattened dermal-epidermal junctions, wrinkles, reduced elasticity and pigmentation issues.

The R&D teams at Biologique Recherche have focused on two key proteins involved in this process, firstly, Progerin, a protein that accumulates with age, disrupting cell regeneration, extracellular matrix integrity and inflammatory responses. This leads to thinning skin, wrinkles and loss of subcutaneous fat, resulting in a gaunt appearance typical of chronological ageing and secondly, Klotho. This is known as the ‘youth protein’ and maintains proper cell function by enhancing skin resistance to oxidative stress and blocking ageing pathways. Unlike progerin, klotho supports skin health and delays cell senescence.

Sérum Progeskin’s formula targets these proteins to combat ageing. Designed to be used around the face, neck and décolleté, it leaves the skin firmer, plumper and more toned, visibly reducing wrinkles and fine lines for a rejuvenated appearance.

Sérum Progeskin features a cutting-edge blend of two active ingredients: Progescence, which decreases progerin synthesis, reducing senescent cell accumulation over time and Pro-KL which activates klotho protein, supporting cellular metabolism and promoting skin cell longevity.

Potent partners
For enhanced anti-ageing results, Biologique Recherche has paired Sérum Progeskin with its renowned Sérum Collagène Originel. This powerful combination addresses established wrinkles and preserves youthful skin.

Launched in 2022, Sérum Collagène Originel targets four primary types of collagen using Type 0 Collagen, silene extract, green microalgae, and soy glycopeptides. Type 0 Collagen, derived from marine jellyfish, is the purest form of collagen, representing the original protein in its raw state.

Working with a marine biotech specialist, Biologique Recherche’s R&D team extracted this ancient collagen to re-densify skin, making it tighter, smoother and plumper, while significantly reducing wrinkle length.

Sérum Collagène Originel specifically addresses established wrinkles, while Sérum Progeskin targets cutaneous ageing. Together, they provide a potent anti-ageing skincare solution.

Dr Philippe Allouche, co-chair and head of creation and R&D at Biologique Recherche, comments: “Sérum Progeskin and Sérum Collagène Originel work in synergy to preserve the skin’s natural youthfulness, delivering a firm and radiant complexion.”

About Biologique Recherche
The science-led brand formulates its products without artificial fragrances in its own laboratory in France. Biologique Recherche is the partner of choice for exceptional spas, medical spas and premier luxury hotels in over 80 countries. Biologique Recherche has its own flagship Ambassades in Paris, Rome, Brussels, Stockholm, Shanghai and Los Angeles.

More: www.biologique-recherche.com/en-gb

Progescence® and Pro-KL® are trademarks of Biologique Recherche
photo: Biologique Recherche

"Sérum Progeskin and Sérum Collagène Originel work in synergy to preserve the skin’s natural youthfulness" – Dr Philippe Allouche, Biologique Recherche

Read more from this issue of Spa Business magazine

View contents of Spa Business 2024 issue 3
The new formula is applied to the face, neck and décolleté
The new formula is applied to the face, neck and décolleté / photo: Biologique Recherche
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ADVERTISE . CONTACT US

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Tel: +44 (0)1462 431385

©Cybertrek 2026

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