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The new facial is available at 111Skin Spa/Clinic partner, The Plaza Hotel in New York City / 111Skin Plaza NYC
Beauty brand 111Skin is introducing one of its most significant scientific advancements with the launch of the Exosome Face Lift, a next-generation lifting and firming treatment designed to deliver clinically-powered results from the convenience of home or spa.
Powered by potent bacterial exosomes derived from probiotic strains to enhance cell-to-cell communication, this sophisticated two-step regime combines an Exosome Shot Serum, infused with microspicules to create micro-channels for deeper penetration, with an Exosome Overnight Mask that boosts repair, collagen production and regeneration during sleep. Over a transformative four week course, the treatment is clinically proven to lift the skin by 20 per cent and improve firmness by 23 per cent, harnessing innovations and clinical protocols from cosmetic clinic 111 Harley St, London, the birthplace of 111Skin.
A new and innovative spa treatment To support this groundbreaking launch, 111Skin has introduced its most advanced spa treatment yet, the Exosome Regeneration Facial, a three-part, 90-minute protocol that uses the same exosometechnology in a relaxing spa setting, incorporating the new Exosome Face Liftproducts
The facial also layers in ultrasonic exfoliation and RF microcurrent toning with the 111Skin Energy Sculpting Device to accelerate cell renewal, lift and firm the skin and restore vitality, with immediate visible results.
This three-part sequence uses the Y Theorem Bio Cellulose Facial Mask and Exosome Overnight Mask, with the Black Diamond Lifting and Firming Mask completing the protocol, delivering a sculpted, regenerated, clinically-elevated finish and immediate glow.
Developed by Dr Yannis Alexandrides, the facial bridges the gap between aesthetics and indulgence, bringing innovation from his exclusive 111 Harley St Clinic to a select group of luxury spa partners.
The brand’s new Exosome launch marks a defining moment in luxury skincare and spa treatment offerings. As regenerative aesthetics continue to shape the future of the industry, 111Skin stands at the forefront with its results-driven skincare and unique approach to spa treatment protocols. l
With over 100 luxury spa partners worldwide, 111Skin continues to expand its influence in science-led wellness. Recent notable partnerships include:
The Plaza Hotel, New York
Mandarin Oriental Downtown Dubai
Caesars Palace, Las Vegas
Fairmont Banff Springs, Canada
Grantley Hall, UK
Mandarin Oriental Sanya, China
Four Seasons Hangzhou, China
Les Grandes Alpes, Courchevel
Dr Yannis Alexandrides, founder, 111Skin 111Skin
Exosomes are at the forefront of regenerative skincare and it’s exciting to bring these advanced technologies to luxurious spa environments – Dr Yannis Alexandrides, founder, 111Skin
Spotlight
111Skin Spa/Clinic at The Plaza Hotel, New York
The opening of the 111Skin Spa/Clinic at The Plaza Hotel is the brand’s first US outpost and a landmark moment for exosome-powered skincare.
The 8,000sq ft sanctuary blends clinical precision with luxury wellness, featuring state-of-the-art treatment rooms, relaxation lounges and exclusive suites.
The new spa offers the full Exosome experience, alongside signature treatments such as the Reparative Longevity Facial, Black Diamond Non-Surgical Lift and Glass Skin Facial, while LED light therapy, cryotherapy, and hydro-infusion complement 111Skin’s clinical protocols, delivering visible results.
Snow improves sleep, supports recovery and builds team spirit 111Skin Plaza NYC
Read more from this issue of Spa Business magazine
Interview: Yoshiharu Hoshino
Backed by US$1.6 billion in assets, the CEO of Hoshino Resorts talks to Katie Barnes about growth strategy and onsen innovation in Japan and beyond
Hotel spa: Nature recharged
Lisa Starr visits Puradies in the Austrian Alps, where thoughtful design and eco spas are having a profound impact on businesses
Research: High achiever
The latest figures from the GWI show the global wellness economy is now worth US$6.8 trillion
Sponsored: Living Earth Crafts – on a mission
Living Earth Crafts already counts leading global operators among its clientele. CEO Jim Chenevey says the company is taking innovation to the next level in 2026
Menu engineering: At your service
Auberge pivots to joy, Oberoi reveals lifestyle framework concept and a gamified therapist training platform launches
Finishing touch: Hot issue
Revised guidelines outline when heat is safe – and when it’s not – for those undergoing cancer treatment
The Spa Life UK Convention returns from 21–23 June 2026 at Whittlebury Park Hotel, Spa &
Golf Resort, bringing together spa managers, directors and owners for two days of focused
education, meaningful connection and commercial insight. [more...]
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COMPANY PROFILES
Sommerhuber GmbH
Sommerhuber specialises in the manufacturing of heat-storing ceramics for spas. [more...]
Knesko Skin
Known for their unique approach to wellness and beauty, Knesko’s products combine ancient healing tr [more...]
The new facial is available at 111Skin Spa/Clinic partner, The Plaza Hotel in New York City / 111Skin Plaza NYC
Beauty brand 111Skin is introducing one of its most significant scientific advancements with the launch of the Exosome Face Lift, a next-generation lifting and firming treatment designed to deliver clinically-powered results from the convenience of home or spa.
Powered by potent bacterial exosomes derived from probiotic strains to enhance cell-to-cell communication, this sophisticated two-step regime combines an Exosome Shot Serum, infused with microspicules to create micro-channels for deeper penetration, with an Exosome Overnight Mask that boosts repair, collagen production and regeneration during sleep. Over a transformative four week course, the treatment is clinically proven to lift the skin by 20 per cent and improve firmness by 23 per cent, harnessing innovations and clinical protocols from cosmetic clinic 111 Harley St, London, the birthplace of 111Skin.
A new and innovative spa treatment To support this groundbreaking launch, 111Skin has introduced its most advanced spa treatment yet, the Exosome Regeneration Facial, a three-part, 90-minute protocol that uses the same exosometechnology in a relaxing spa setting, incorporating the new Exosome Face Liftproducts
The facial also layers in ultrasonic exfoliation and RF microcurrent toning with the 111Skin Energy Sculpting Device to accelerate cell renewal, lift and firm the skin and restore vitality, with immediate visible results.
This three-part sequence uses the Y Theorem Bio Cellulose Facial Mask and Exosome Overnight Mask, with the Black Diamond Lifting and Firming Mask completing the protocol, delivering a sculpted, regenerated, clinically-elevated finish and immediate glow.
Developed by Dr Yannis Alexandrides, the facial bridges the gap between aesthetics and indulgence, bringing innovation from his exclusive 111 Harley St Clinic to a select group of luxury spa partners.
The brand’s new Exosome launch marks a defining moment in luxury skincare and spa treatment offerings. As regenerative aesthetics continue to shape the future of the industry, 111Skin stands at the forefront with its results-driven skincare and unique approach to spa treatment protocols. l
With over 100 luxury spa partners worldwide, 111Skin continues to expand its influence in science-led wellness. Recent notable partnerships include:
The Plaza Hotel, New York
Mandarin Oriental Downtown Dubai
Caesars Palace, Las Vegas
Fairmont Banff Springs, Canada
Grantley Hall, UK
Mandarin Oriental Sanya, China
Four Seasons Hangzhou, China
Les Grandes Alpes, Courchevel
Dr Yannis Alexandrides, founder, 111Skin 111Skin
Exosomes are at the forefront of regenerative skincare and it’s exciting to bring these advanced technologies to luxurious spa environments – Dr Yannis Alexandrides, founder, 111Skin
Spotlight
111Skin Spa/Clinic at The Plaza Hotel, New York
The opening of the 111Skin Spa/Clinic at The Plaza Hotel is the brand’s first US outpost and a landmark moment for exosome-powered skincare.
The 8,000sq ft sanctuary blends clinical precision with luxury wellness, featuring state-of-the-art treatment rooms, relaxation lounges and exclusive suites.
The new spa offers the full Exosome experience, alongside signature treatments such as the Reparative Longevity Facial, Black Diamond Non-Surgical Lift and Glass Skin Facial, while LED light therapy, cryotherapy, and hydro-infusion complement 111Skin’s clinical protocols, delivering visible results.
Snow improves sleep, supports recovery and builds team spirit 111Skin Plaza NYC
Read more from this issue of Spa Business magazine
Interview: Yoshiharu Hoshino
Backed by US$1.6 billion in assets, the CEO of Hoshino Resorts talks to Katie Barnes about growth strategy and onsen innovation in Japan and beyond
Hotel spa: Nature recharged
Lisa Starr visits Puradies in the Austrian Alps, where thoughtful design and eco spas are having a profound impact on businesses
Research: High achiever
The latest figures from the GWI show the global wellness economy is now worth US$6.8 trillion
Sponsored: Living Earth Crafts – on a mission
Living Earth Crafts already counts leading global operators among its clientele. CEO Jim Chenevey says the company is taking innovation to the next level in 2026
Menu engineering: At your service
Auberge pivots to joy, Oberoi reveals lifestyle framework concept and a gamified therapist training platform launches
Finishing touch: Hot issue
Revised guidelines outline when heat is safe – and when it’s not – for those undergoing cancer treatment
A recent survey by the UK Spa Association (UKSA) into the industry’s approach to cancer care
has revealed that almost half of participating respondents (46 per cent) are unaware that
cancer is a disability and guests with a cancer diagnosis must be given
Mexican operator, Solmar Hotels and Resorts, is hosting a series of events in celebration of
Global Wellness Day, including a Temazcal ceremony at its Playa Grande Resort and Spa in Los
Cabos.
Mandarin Oriental has announced a standalone residence brand, Mansions, which will debut at
Emirates Palace, Mandarin Oriental Mansions, Abu Dhabi, in 2029.
Four Seasons Resort The Nam Hai in Hoi An, Vietnam, has put together a Global Wellness Day
(GWD) agenda with activations rooted in nature and shaped by four pillars of Joy – in
alignment with the day’s theme #JoyMagenta.
The Global Wellness Summit (GWS) will celebrate its 20th anniversary at the 2026 event in
Phuket, Thailand, later this year with the theme: The Science, Art and Soul of Wellness.
Auko, an all-inclusive development, is opening in Phong Nha in Vietnam in Q3 2026, with a
series of 30 tented eco-lodges and wellness hospitality operations by Lumina Wellbeing.
Therme Manchester’s 28-acre development, which will include interconnected glass pavilions
that measure 65,000sq m, will be the largest bathing and wellbeing attraction in the world once
complete, according to prof David Russell, CEO of Therme UK.
Naples Beach Club, a Four Seasons Resort, has opened a 2,800sq m spa called The Sanctuary,
with the design and concept inspired by the Native American people that populated Florida’s
Southwest coast – the Calusa.
The Spa Life UK Convention returns from 21–23 June 2026 at Whittlebury Park Hotel, Spa &
Golf Resort, bringing together spa managers, directors and owners for two days of focused
education, meaningful connection and commercial insight. [more...]
+ More featured suppliers
COMPANY PROFILES
Sommerhuber GmbH Sommerhuber specialises in the manufacturing of heat-storing ceramics for spas. [more...]