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111Skin - Restoring vitality

111Skin is taking exosome-driven skin rejuvenation to the next level with new launches


Beauty brand 111Skin is introducing one of its most significant scientific advancements with the launch of the Exosome Face Lift, a next-generation lifting and firming treatment designed to deliver clinically-powered results from the convenience of home or spa.

Powered by potent bacterial exosomes derived from probiotic strains to enhance cell-to-cell communication, this sophisticated two-step regime combines an Exosome Shot Serum, infused with microspicules to create micro-channels for deeper penetration, with an Exosome Overnight Mask that boosts repair, collagen production and regeneration during sleep. Over a transformative four week course, the treatment is clinically proven to lift the skin by 20 per cent and improve firmness by 23 per cent, harnessing innovations and clinical protocols from cosmetic clinic 111 Harley St, London, the birthplace of 111Skin.

A new and innovative spa treatment
To support this groundbreaking launch, 111Skin has introduced its most advanced spa treatment yet, the Exosome Regeneration Facial, a three-part, 90-minute protocol that uses the same exosome  technology in a relaxing spa setting, incorporating the new Exosome Face Lift  products

The facial also layers in ultrasonic exfoliation and RF microcurrent toning with the 111Skin Energy Sculpting Device to accelerate cell renewal, lift and firm the skin and restore vitality, with immediate visible results.

This three-part sequence uses the Y Theorem Bio Cellulose Facial Mask and Exosome Overnight Mask, with the Black Diamond Lifting and Firming Mask completing the protocol, delivering a sculpted, regenerated, clinically-elevated finish and immediate glow.

Developed by Dr Yannis Alexandrides, the facial bridges the gap between aesthetics and indulgence, bringing innovation from his exclusive 111 Harley St Clinic to a select group of luxury spa partners.

The brand’s new Exosome launch marks a defining moment in luxury skincare and spa treatment offerings. As regenerative aesthetics continue to shape the future of the industry, 111Skin stands at the forefront with its results-driven skincare and unique approach to spa treatment protocols. l

More: www.111skin.com

111SKIN Global Momentum
With over 100 luxury spa partners worldwide, 111Skin continues to expand its influence in science-led wellness. Recent notable partnerships include:
  • The Plaza Hotel, New York
  • Mandarin Oriental Downtown Dubai
  • Caesars Palace, Las Vegas
  • Fairmont Banff Springs, Canada
  • Grantley Hall, UK
  • Mandarin Oriental Sanya, China
  • Four Seasons Hangzhou, China
  • Les Grandes Alpes, Courchevel
Dr Yannis Alexandrides, founder, 111Skin
Dr Yannis Alexandrides, founder, 111Skin 111Skin

Exosomes are at the forefront of regenerative  skincare and it’s exciting to bring these advanced technologies to luxurious spa environments
Dr Yannis Alexandrides, founder, 111Skin

Spotlight
111Skin Spa/Clinic at The Plaza Hotel, New York

The opening of the 111Skin Spa/Clinic at The Plaza Hotel is the brand’s first US outpost and a landmark moment for exosome-powered skincare.

The 8,000sq ft sanctuary blends clinical precision with luxury wellness, featuring state-of-the-art treatment rooms, relaxation lounges and exclusive suites.

The new spa offers the full Exosome experience, alongside signature treatments such as the Reparative Longevity Facial, Black Diamond Non-Surgical Lift and Glass Skin Facial, while LED light therapy, cryotherapy, and hydro-infusion complement 111Skin’s clinical protocols, delivering visible results.

Snow improves sleep, supports recovery and builds team spirit
Snow improves sleep, supports recovery and builds team spirit 111Skin Plaza NYC

Read more from this issue of Spa Business magazine

View contents of Spa Business 2025 issue 4
111Skin’s Exosome products are used in the new facial
111Skin’s Exosome products are used in the new facial / 111Skin Plaza NYC
FEATURED SUPPLIERS

Longevity in spas: a strategic choice, not a default setting
Longevity has become one of the most debated concepts in contemporary wellness. [more...]

Why future-ready in-house laundry is the new luxury spa essential
In today’s premium spa environment, every detail shapes the guest experience – right down to the softness of towels and the freshness of linens. [more...]
+ More featured suppliers  
COMPANY PROFILES
We Work Well Inc

In 2019 Monica Helmstetter and Lucy Hugo founded the American hosted buyer event company We Work Wel [more...]
FIBO

FIBO is the international platform for fitness, wellness and health. During four days, FIBO connects [more...]
+ More profiles  
CATALOGUE GALLERY
 

+ More catalogues  

DIRECTORY
+ More directory  
DIARY

 

03-05 Jul 2026

World Championship in Massage

Copenhagen, Copenhagen, Denmark
23-26 Aug 2026

Elevate Spa Riviera Maya Edition

The Riviera Maya Edition Kanai, Playa del Carmen, Mexico
+ More diary  
 
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©Cybertrek 2026
Uniting the world of spa & wellness
Get Spa Business and Spa Business insider digital magazines FREE
Sign up here ▸
News   Products   Magazine   Subscribe
Sponsored
111Skin - Restoring vitality

111Skin is taking exosome-driven skin rejuvenation to the next level with new launches


Beauty brand 111Skin is introducing one of its most significant scientific advancements with the launch of the Exosome Face Lift, a next-generation lifting and firming treatment designed to deliver clinically-powered results from the convenience of home or spa.

Powered by potent bacterial exosomes derived from probiotic strains to enhance cell-to-cell communication, this sophisticated two-step regime combines an Exosome Shot Serum, infused with microspicules to create micro-channels for deeper penetration, with an Exosome Overnight Mask that boosts repair, collagen production and regeneration during sleep. Over a transformative four week course, the treatment is clinically proven to lift the skin by 20 per cent and improve firmness by 23 per cent, harnessing innovations and clinical protocols from cosmetic clinic 111 Harley St, London, the birthplace of 111Skin.

A new and innovative spa treatment
To support this groundbreaking launch, 111Skin has introduced its most advanced spa treatment yet, the Exosome Regeneration Facial, a three-part, 90-minute protocol that uses the same exosome  technology in a relaxing spa setting, incorporating the new Exosome Face Lift  products

The facial also layers in ultrasonic exfoliation and RF microcurrent toning with the 111Skin Energy Sculpting Device to accelerate cell renewal, lift and firm the skin and restore vitality, with immediate visible results.

This three-part sequence uses the Y Theorem Bio Cellulose Facial Mask and Exosome Overnight Mask, with the Black Diamond Lifting and Firming Mask completing the protocol, delivering a sculpted, regenerated, clinically-elevated finish and immediate glow.

Developed by Dr Yannis Alexandrides, the facial bridges the gap between aesthetics and indulgence, bringing innovation from his exclusive 111 Harley St Clinic to a select group of luxury spa partners.

The brand’s new Exosome launch marks a defining moment in luxury skincare and spa treatment offerings. As regenerative aesthetics continue to shape the future of the industry, 111Skin stands at the forefront with its results-driven skincare and unique approach to spa treatment protocols. l

More: www.111skin.com

111SKIN Global Momentum
With over 100 luxury spa partners worldwide, 111Skin continues to expand its influence in science-led wellness. Recent notable partnerships include:
  • The Plaza Hotel, New York
  • Mandarin Oriental Downtown Dubai
  • Caesars Palace, Las Vegas
  • Fairmont Banff Springs, Canada
  • Grantley Hall, UK
  • Mandarin Oriental Sanya, China
  • Four Seasons Hangzhou, China
  • Les Grandes Alpes, Courchevel
Dr Yannis Alexandrides, founder, 111Skin
Dr Yannis Alexandrides, founder, 111Skin 111Skin

Exosomes are at the forefront of regenerative  skincare and it’s exciting to bring these advanced technologies to luxurious spa environments
Dr Yannis Alexandrides, founder, 111Skin

Spotlight
111Skin Spa/Clinic at The Plaza Hotel, New York

The opening of the 111Skin Spa/Clinic at The Plaza Hotel is the brand’s first US outpost and a landmark moment for exosome-powered skincare.

The 8,000sq ft sanctuary blends clinical precision with luxury wellness, featuring state-of-the-art treatment rooms, relaxation lounges and exclusive suites.

The new spa offers the full Exosome experience, alongside signature treatments such as the Reparative Longevity Facial, Black Diamond Non-Surgical Lift and Glass Skin Facial, while LED light therapy, cryotherapy, and hydro-infusion complement 111Skin’s clinical protocols, delivering visible results.

Snow improves sleep, supports recovery and builds team spirit
Snow improves sleep, supports recovery and builds team spirit 111Skin Plaza NYC

Read more from this issue of Spa Business magazine

View contents of Spa Business 2025 issue 4
111Skin’s Exosome products are used in the new facial
111Skin’s Exosome products are used in the new facial / 111Skin Plaza NYC
LATEST NEWS
HCM News: Taking GLP-1s is linked to a decline in physical activity
People taking GLP-1 weight loss medications such as Ozempic, Wegovy, Mounjaro and Zepbound may be losing weight, but they’re also becoming less physically active, according to new research presented at the ENDO 2026 annual meeting of the Endocrine Society
Mubadala makes €1 billion bid for Pierre and Vacances
Abu Dhabi-based investment firm Mubadala Capital has made a binding, fully financed €1 billion offer to acquire Pierre and Vacances SA, the European holiday resort operator behind the continental European Center Parcs business.
Synergy The Retreat Show launches resource for retreat business leaders to showcase specialisms
Global retreat trade show, Synergy The Retreat Show, has launched a resource called The Source, which hosts an open-access online Transformation Series programme.
The SATCC announces first five-day Living with Cancer and Beyond retreat
The Standards Authority for Touch in Cancer Care (SATCC) charity has announced its first five- day Living with Cancer and Beyond retreat, which will be held at Carden Park Hotel and Spa in Cheshire, UK, between 1 and 5 September.
Palazzo di Varignana launches family wellbeing and longevity retreat in Emilia Romagna
Palazzo di Varignana, in the Emilia Romagna region of Italy, has created a new tailored health programme designed specifically for families.
Ansana Wellness and Spa debuts at Patmos Aktis as it joins Marriott
Patmos Aktis, a Luxury Collection Resort and Spa, has opened in Greece, with a renovated and rebranded wellness offering called Ansana Wellness and Spa.
Mauna Kea Beach Hotel launches destination spa with sacred Hawaiian cultural concept
The Mauna Kea Beach Hotel, an Autograph Collection property in Hawaii, US, has opened its 22,000 sq ft indoor-outdoor Spa at Mauna Kea as the final step in the property’s overall renovation, which has cost more than US$180 million (€166 million, £140 mill
The Good Spa Guide sets up event for modified Good Spa Guide Awards
The UK spa review and discovery platform for consumers, the Good Spa Guide, has announced it will host the Good Spa Guide Awards 2026 during an event on 16 November at Sopwell House Hotel in St Albans, UK.
McKinsey: 84 per cent of consumers say wellness is a top priority
Eighty-four per cent of consumers now say wellness is a top priority in their lives, with this percentage increasing year on year, according to a preview presentation of McKinsey’s Future of Wellness 2026 research report.
Protests continue in Albania against US$1.6 billion luxury resort backed by Jared Kushner and Ivanka Trump
Mass protests have been taking place since Monday 1 June in Albania over the development of a luxury resort by Donald Trump’s daughter Ivanka Trump and her husband Jared Kushner.
Barons Eden rebrands to Hiddenwell ahead of spa hotel portfolio expansion
Barons Eden, the UK parent company that operates luxury destination properties in England, has rebranded to become Hiddenwell.
Belgin Aksoy marks 15 years of Global Wellness Day
Global Wellness Day (GWD) marked its 15th anniversary on Saturday 13 June 2026, with the theme: #JoyMagenta – a celebration of the healing qualities of simple gestures and activities that spark joy.
+ More news   
 
FEATURED SUPPLIERS

Longevity in spas: a strategic choice, not a default setting
Longevity has become one of the most debated concepts in contemporary wellness. [more...]

Why future-ready in-house laundry is the new luxury spa essential
In today’s premium spa environment, every detail shapes the guest experience – right down to the softness of towels and the freshness of linens. [more...]
+ More featured suppliers  
COMPANY PROFILES
We Work Well Inc

In 2019 Monica Helmstetter and Lucy Hugo founded the American hosted buyer event company We Work Wel [more...]
+ More profiles  
CATALOGUE GALLERY
+ More catalogues  

DIRECTORY
+ More directory  
DIARY

 

03-05 Jul 2026

World Championship in Massage

Copenhagen, Copenhagen, Denmark
23-26 Aug 2026

Elevate Spa Riviera Maya Edition

The Riviera Maya Edition Kanai, Playa del Carmen, Mexico
+ More diary  
 


ADVERTISE . CONTACT US

Leisure Media
Tel: +44 (0)1462 431385

©Cybertrek 2026

ABOUT LEISURE MEDIA
LEISURE MEDIA MAGAZINES
LEISURE MEDIA HANDBOOKS
LEISURE MEDIA WEBSITES
LEISURE MEDIA PRODUCT SEARCH
PRINT SUBSCRIPTIONS
FREE DIGITAL SUBSCRIPTIONS